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Completed

NCT Number: NCT00535964

Evaluating the Relationship Between Tobacco Use, Anxiety Sensitivity, and Panic in Adolescents

This study will determine whether there is a relationship between tobacco use and a heightened response to panic-producing events among adolescents. This study is fundamental research. It was not a Clinical Trial.

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Key information

Age range

12 year–17 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Arkansas

Fayetteville, Arkansas, 72701, United States

About this study

Growing up is hard enough, and adolescence can be a particularly stressful time in people's lives as they adjust to the transition from childhood to adulthood. Peer pressure can add to this anxiety, making it more likely for teens to take part in risky behaviors such as smoking cigarettes. Every day, more than 4,000 teens smoke their first cigarette and nearly half of those teens will become regular, daily smokers. Cigarette smoking is associated with a multitude of health risks, including an increased likelihood of experiencing panic attacks, anxiety disorders, and depression. This study will evaluate a group of teens, ranging from those who have never smoked to those who smoke daily, to determine whether there is a relation between adolescent smoking history and their vulnerability to panic-producing situations.

Participants in this study will undergo a brief medical screening, followed by a short interview that will include several questionnaires regarding emotions, experiences, and personal habits. Participants will then attend a series of laboratory assessments for 1 hour. The first assessment will include a 3-minute voluntary hyperventilation procedure in which participants will be directed when to breathe in and when to breathe out, at a faster rate than normal. Participants will then take part in two computerized tasks: one will be a computerized task that involves blowing up a balloon and deciding when to quit before the balloon pops; the other task will involve choosing hypothetical amounts of money now or after a period of delay. During the laboratory assessments, all participants will have electrodes attached to their bodies and sensors around their chests to measure heart rate, palm sweating, and muscle tension. Results from this study will be used to evaluate the association between smoking and increased panic levels under stressful conditions among adolescents.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adolescents, ranging from those who have never smoked to those who smoke daily

Exclusion criteria

  • Current or past diagnosis of a panic disorder
  • Acute or chronic cardiopulmonary or respiratory illness (e.g., asthma or bronchitis)
  • Pregnant

Treatment and study plan

Primary outcomes

  1. Relationship between cigarette smoking and panic vulnerability

    Time frame: Measured at completion of laboratory testing analysis

Sponsors and collaborators

Lead sponsor

University of Arkansas, Fayetteville

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Official study title

Anxiety Sensitivity, Tobacco Use, and Panic Among Adolescents

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
Sep 27, 2007
Registry last updated
Nov 17, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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