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Completed

NCT Number: NCT07482449

Evaluating the Effectiveness of Postoperative Analgesic Methods in Thoracotomy Cases

Effective control of severe post-thoracotomy pain is pivotal for minimizing pulmonary complications and enhancing patient comfort. This prospective, randomized, three-arm study compared the analgesic efficacy of ultrasound-guided bilateral erector spinae plane block (ESPB) and thoracic epidural analgesia (TEA) with conventional intravenous opioid-based care. Seventy-two ASA I-II patients aged 18-80 years undergoing elective thoracotomy were block-randomized to receive TEA, ESPB, or no regional intervention (control). All procedures were performed at the end of surgery before emergence from anesthesia. Pain intensity was assessed at 1, 2, 4, 6, 12, and 24 h postoperatively using the Visual Analog Scale (VAS). Additional outcomes included time to first rescue opioid, total tramadol consumption, time to modified Aldrete score (MAS) ≥ 9, patient satisfaction, and length of hospital stay.

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Key information

Conditions

Thoracotomy Analgesia

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Trakya University Faculty of Medicine Hospital

Edirne, Merkez, 22020, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ASA I-II, Age Range 18-80 years old

-

Exclusion criteria

GKS < 15 LIVER, HEART, LUNG, KIDNEY FAILURE PREGNANCY TRAUMA NEUROLOGICAL DEFICIT

Treatment and study plan

Primary outcomes

  1. Comparison of the analgesic efficacy of regional techniques

    Time frame: THE FIRST 24 HOURS AFTER THORACOTOMY SURGERY

    The analgesic efficacy of TEA and ESP blocks after thoracotomy surgeries was evaluated at 1, 2, 4, 6, 12, and 24 hours postoperatively in terms of VAS scores and analgesic drug consumption. The frequency and amount of tramadol and fentanyl analgesic drug consumption were recorded in the postoperative period. VAS scores were monitored at the specified times. The results were compared, and analgesic efficacy was evaluated. In addition, patient satisfaction (1: excellent, 2: good, 3: moderate, 4: poor), intensive care unit and hospital stay, and postoperative recovery time (using the modified aldarate score) were evaluated.

Sponsors and collaborators

Lead sponsor

Denizhan Acar

Other

Registry information

Official study title

Comparison of the Effectiveness of Ultrasound-Guided Bilateral Erector Spinae Plane Block and Thoracic Epidural Analgesia Methods in Patients Undergoing Thoracotomy

Important dates

Study start
2023
Primary completion
2025
Study completion
2026
First posted
Mar 19, 2026
Registry last updated
Mar 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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