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NCT Number: NCT07131267

Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study

Both sexual experiences and the process of gender transition initiated to reduce gender dysphoria carry cultural characteristics. Gender categories, societal expectations for each gender, and attitudes toward sexual minorities in a given society can shape the lived experiences of trans individuals. Therefore, research on individuals with gender dysphoria in different cultural contexts is of great importance. To our knowledge, no study in Türkiye has examined sexual functioning in trans individuals undergoing gender transition. For this reason, our study aimed to investigate how sexual functioning is affected by the gender transition process in trans men with gender dysphoria, using both quantitative and qualitative methods.

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Key information

Age range

18 year–65 year

Sex eligibility

Female

Study type

Observational

Primary location

Eskişehir Osmangazi University, Faculty of Medicine, Department of Psychiatry

Eskişehir, Türkiye, 26040, Turkey (Türkiye)

Location status: Recruiting

Location contact

Aylin Aydin, Assisst.Dr.

CONTACT

[email protected]

00902222392979 ext. 3600

Imran G Yilmaz-Karaman, Assoc.Prof.

CONTACT

[email protected]

00902222392979 ext. 3604

About this study

For the quantitative part of the study, 52 participants will receive a sociodemographic and clinical data form, Arizona Sexual Experiences Scale, Sexual Desire Inventory, Utrecht Gender Dysphoria Scale, Depression Anxiety Stress Scale-21, and WHOQOL-100 sexual quality of life subscale.

While performing a qualitative study, 12 participants will receive questions about their sexual functioning during the gender affirmation process.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 years or older Diagnosed with gender dysphoria by two different physicians Getting medical support for the gender affirmation process

Exclusion criteria

Over 65 years Diagnosed with intellectual disability, dementia, or organic mental disorders Having a systemic disease that negatively impacts sexual function Getting a score above 3 on the Clinical Global Impression Scale

Treatment and study plan

Primary outcomes

  1. Sexual functioning

    Time frame: Day 1

    Arizona Sexual Experience Scale: It is designed to measure five specific items identified as fundamental elements of sexual function. The scale was designed by McGahuey (McGahuey et al., 1997). The Turkish validity and reliability of the scale was conducted by Atilla Soykan (Soykan, 2004). Higher scores indicate higher levels of dysfunction.

  2. Sexual desire

    Time frame: Day 1

    Sexual Desire Inventory-2: It is a 14-item, self-administered questionnaire measuring sexual desire (Spector et al., 1996). It includes subscales of sexual motivation, sexual satisfaction, sexual relationship quality, activity frequency, and behavioral diversity to capture the multidimensional nature of sexual desire. The Turkish validity and reliability of the scale, along with other languages, were conducted in Castro-Calvo's study (Castro-Calvo et al., 2024). High scores indicate high sexual desire.

Study contacts

Contact information is provided by the study sponsor or research team.

Aylin Aydin, Assist.Dr.

CONTACT

[email protected]

02222392979 ext. 3600

Imran G Yilmaz-Karaman, Assoc.Prof.

CONTACT

[email protected]

02222392979 ext. 3600

Sponsors and collaborators

Lead sponsor

Eskisehir Osmangazi University

Other

Registry information

Acronym: ESFTMGAP

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 20, 2025
Registry last updated
Aug 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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