Evaluating Benefit of Peptide Based Diet in Obese HEN Patients

Change in body weight, measured in kg

Change in lean body mass, measured as the difference between total body weight and body fat weight reported in percentage

Change in systolic and diastolic blood pressure, measured in mmHg

Change in hemoglobin A1c, measured in percentage

Change in c-peptide serum levels, measured in ng/mL

Change in total cholesterol, measured in milligrams (mg) of cholesterol per deciliter (dL) of blood.

Change in HDL, measured in milligrams (mg) of HDL per deciliter (dL) of blood.

Change in LDL, measured in milligrams (mg) of LDL per deciliter (dL) of blood.

Change in triglycerides, measured in milligrams (mg) of triglycerides per deciliter (dL) of blood.

Change in percent goal calories provided with enteral nutrition , measured percent of calorie provided with enteral nutrition from the estimated goal.

Change in percent goal proteins provided with enteral nutrition , measured percent of protein provided with enteral nutrition from the estimated goal.

Change in tolerance to tube feeding, measured by follow up questionnaire about symptoms of GI intolerance; namely, diarrhea, constipation, abdominal(stomach/tummy/belly) pain or discomfort, nausea and vomiting. The scale used will asses the frequency of these symptoms using the following terms: not at all, rarely, sometimes, often, and very often with not at all being least frequent and very often being most frequent presence of the concerning symptom.

Change in hand grip strength, measured by dynamometer.

Change in diabetes medications, measured by capturing any change in diabetes medications (when applicable) in terms of new medications added, or discontinuation or change in doses of current medications.

Change in hypertension medications, measured by capturing any change in hypertension medications (when applicable) in terms of new medications added, or discontinuation or change in doses of current medications.