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NCT Number: NCT07312799

Evaluate the Pharmacokinetic Interaction and the Safety of AD-2321 and AD-2322

To evaluate the pharmacokinetic interactions of AD-2321, AD-2322 in healthy adult volunteers.

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

19 year–64 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adult volunteers aged ≥19 and <65 years at the time of the screening visit
  • Body weight ≥50 kg (≥45 kg for females) and body mass index (BMI) between 18.0 kg/m² and 30.0 kg/m² at the time of the screening visit

Exclusion criteria

  • Participation in another clinical study with an investigational drug within the 6 months from scheduled first administration
  • Other exclusions applied

Treatment and study plan

Treatment A(AD-2321)

Drug

AD-2321 Oral Tablet

Treatment B(AD-2322)

Drug

AD-2322 Oral Tablet

Treatment C(AD-2321+AD-2322)

Drug

AD-2321 Oral Tablet+AD-2322 Oral Tablet

Primary outcomes

  1. Area under the plasma concentration-time curve during dosing interval at steady state (AUCτ,ss)

    Time frame: pre-dose (0hour) to 24 hours post-dose on Day 14

    AUCτ,ss

  2. Maximum concentration of drug in plasma at steady state (Cmax,ss)

    Time frame: pre-dose (0hour) to 24 hours post-dose on Day 14

Study contacts

Contact information is provided by the study sponsor or research team.

SoonKeun Kwon

CONTACT

[email protected]

+82318916915

Sponsors and collaborators

Lead sponsor

Addpharma Inc.

Industry

Registry information

Official study title

A Two-arm, Open-label, Single-sequence, Multiple-dose Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-2321 and AD-2322 in Healthy Adult Volunteers

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Dec 31, 2025
Registry last updated
Dec 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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