Evaluate the Efficacy and Safety of My-Rept® Tablet vs. My-Rept® Capsule in Combination With Tacrolimus in Kidney Transplant Patients

Inclusion criteria

• Age 20 years or older.
• Patient who receive primary or secondary kidney transplantation from living or brain-dead donor .
• Patient who receive age 20 years or older donor.
• Willing and able to provide written informed consent.

Exclusion criteria

• Cold Ischemia Time > 30 hours.
• Patient who receive HLA-identical donor.
• Patient with dual kidney transplantation recipient or have history of other organ transplantation in past or current.
• Patient who receive extra-renal solid organ or bone marrow stem cell transplantation.
• Patient who receive kidney transplantation from non-heart beating cadaveric donor(organ donor after cardiac death
• Patient who receive kidney transplantation from ABO blood type mismatching donor or lymphocyte cross matching (LCM) positive donor.
• Patient with cancer within 5 years, except cured skin cancer patient(Squamous cell or basal cell carcinoma)
• Positive in serology test(HIV, HBsAg, HCV) in recipients and/or donor.
• Patient with Severe gastrointestinal disease in screening period by investigator's decision.
• Patient with systemic severe infection requiring treatment (able to transplantation after completely disappear or is controlled infection)
• Liver cirrhosis, clinically significant portal hypertension or other moderate to severe liver disease.
• Defined by the following laboratory parameters before screening period

• One of liver function test(AST, ALT, ALP, Total Bilirubin)results increased more than 3 times upper limit of normal range
• WBC <2,500/mm3, Platelet <75,000/mm3
• Acute (within 4 weeks) or chronic(need to treatments) allergic/hypersensitivity reaction in the history of Investigational drugs (ex, mycophenolate acid or tacrolimus, etc.) or additives.
• Administration of other Investigational drugs and/or immunosuppressants within 28days before screening period (except allowed immunosuppressants in protocol)
• Women in pregnant or breast-feeding or don't using adequate contraception.
• Patient has conversation impairment because alcohol or drugs addiction history within 6months or mental illness, etc.
• In investigator's judgment