EUS- and US- Guided Biopsy for Pancreatic Lesion

Endoscopic ultrasound (EUS) and ultrasound (US) are the two primary imaging modalities used to guide pancreatic needle biopsy. This study aimed to compare the diagnostic performance and complications associated with EUS- and US-guided pancreatic biopsies.

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Key information

Conditions

Pancreatic Cancer Digestive System Diseases Digestive System Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Neoplasms Neoplasms by Site Pancreatic Diseases Pancreatic Neoplasms

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Between January 2017 and December 2023, 2663 consecutive patients with focal pancreatic disease underwent 2729 procedures for pancreatic tissue acquisition from focal pancreatic lesions at seven university teaching hospitals in China.

Exclusion criteria

Patients were excluded from the study if they had less than 12 months of follow-up, were lost to follow-up, had incomplete follow-up data, or underwent intraoperative biopsy or fluid aspiration.

Treatment and study plan

sampling tissue

Other

EUS- and US- guided pancreatic biopsy

Primary outcomes

diagnostic inaccuracy

Time frame: 1-year

Sponsors and collaborators

Lead sponsor

Tian'an Jiang

Other

Registry information

Official study title

Comparison of Safety and Effectiveness Between Endoscopic Ultrasound-guided and Ultrasound-guided Pancreatic Biopsy in Focal Pancreatic Disease: A Multi-center, Retrospective, Propensity Score Analysis

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Aug 24, 2025
Registry last updated: Aug 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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