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Completed

NCT Number: NCT05626647

Etiology of Anemia Among Preschool Children in Ethiopia

This study aims to determine the etiology of anemia among preschool children in selected regions of Ethiopia. The study is a longitudinal observational study to assess the determinant factors of anemia in two different seasons.

The main questions it aims to answer are:

1. What is the prevalence and etiology of anemia in the two different (Post and Pre-harvest) seasons? 2. What is the strength of the interaction between anemia and each of the determinant factors being considered?

The participant's dietary intake and anthropometric measurement have been assessed, and biological samples (Blood and Stool) were collected to determine the prevalence of anemia and the factors contributing to it.

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Key information

Age range

6 month–59 month

Sex eligibility

All sexes

Study type

Observational

Primary location

Ethiopian Public Health Institute

Addis Ababa, Ethiopia

About this study

Background: Although the country made a significant change in the burden of malnutrition in all its forms in the past two decades, the issue remains unacceptably high across all regions of Ethiopia. The national prevalence of anemia among children 6-59 months was very high 57% and one of the public health concerns in 2016. Although the country is known as a data-rich country, in some specific indicators, there is a lack of data and evidence to alleviate the nutritional gaps through an informed decision-making process. In this particular case, there is a lack of evidence relating to child anemia in Ethiopia, especially since there is no comprehensive information about the determinant factors of anemia.

Objective: The objective of the current survey is to determine the etiology of anemia and its public health implications among under-five children in selected ecological zones of Ethiopia at different seasons.

Method: This survey will be a community-based, longitudinal panel study and will be conducted in two different (post-harvest and pre-harvest) seasons in the 2014 Ethiopian calendar year. A nationally representative sample was calculated and allocated to three purposely selected regions (Amhara, Southern Nation, Nationalities, and Peoples' Region (SNNPR), and Somali) in consideration of three different ecological zones (lowlands, midlands, and highlands). The study population will be children aged 6 - 59 months with caregivers/mothers with a sample size of 1212 under-five children from 1212 households. The indicators collected for the survey are dietary intake, anthropometric measurement, and biological samples (Blood and Stool).

Expected benefit: The findings of this survey will provide information on the etiology of anemia that will inform short-term policy decisions, especially for case-specific nutrition-sensitive interventions, and that will contribute to long-term policy decisions for comprehensive nutrition intervention programs.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children 6-53 months during the baseline survey and who have stayed more than 6 months in the selected household of the Amhara or SNNPR or Somali regions of Ethiopia and have no plan to move from the study area during the study period

Exclusion criteria

  • Children older than the youngest child between 6-53 months of age (If more than one eligible child is in the Household) during the baseline survey.
  • Children with severe illness
  • Guests
  • If participants lose their willingness to participate in this study

Treatment and study plan

Primary outcomes

  1. Prevalence of anemia among preschool children in selected regions of Ethiopia in the two different (Post and Pre harvest) seasons?

    Time frame: From November 2021 to September 2022

    Blood hemoglobin level below 11mg/dL

Secondary outcomes

  1. Factors contributing to anemia anemia among preschool children in selected regions of Ethiopia in the two different (Post and Pre harvest) seasons?

    Time frame: From November 2021 to September 2022

    Micronutrient deficiency, presence of infectious disease, and genetic problems contributing to low hemoglobin concentration.

Sponsors and collaborators

Lead sponsor

Oklahoma State University

Other

Collaborators

  • Addis Ababa University
  • Ethiopian Public Health Institute

Registry information

Official study title

Etiology of Anemia Among Preschool Children and Its Public Health Implication in Selected Regions of Ethiopia: A Community-Based Longitudinal Study

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Nov 25, 2022
Registry last updated
Nov 29, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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