Etiology, Epidemiology and Prognostics of Acute Kidney Injury (AKI)

• to investigate the relationship between preexisting malnutrition and adverse outcomes in patients with AKI

• Several nutritional assessment methods such as anthropometric, clinical and biochemical evaluations have been used; however, no single indicator is considered to be a "gold standard."
• to evaluate the association of serum nutritional variables and prognosis of acute kidney injury
• Given the different half-lives of serum nutritional markers, we hypothesized that the utility of serum nutritional variables as prognostic predictors may differ in early death (<7 days) and late death (>7 days, <28 days) patients.

Inclusion criteria

• age >=16 years and <= 88 years
• clinically diagnosed with acute kidney injury, according RIFLE or KDIGO criteria.

Exclusion criteria

• acute Renal Failure occurring in the setting of burns, obstructive uropathy, allergic interstitial nephritis, acute or rapidly progressive glomerulonephritis, vasculitis, hemolytic-uremic syndrome, thrombotic thrombocytopenic purpura (TTP), malignant hypertension, scleroderma renal crisis, atheroembolism, functional or surgical nephrectomy, hepatorenal syndrome, cyclosporin or tacrolimus nephrotoxicity
• Do Not Resuscitate (DNR) status
• subjects enrolled in another clinical trial that could affect the outcome of this study protocol