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Completed

NCT Number: NCT03352336

Estimation of Perioperative Atelectasis

This study will compare an oxygenation test based on arterial blood gas analysis with computed tomography for estimating the extent of atelectasis.

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Key information

Conditions

Atelectasis Lung Diseases Oxygenation Pulmonary Atelectasis Respiratory Tract Diseases

Age range

40 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Västmanlands sjukhus Köping

Köping, Västmanland County, 73181, Sweden

About this study

Computed tomography of the lungs is the gold standard for investigating the extent of atelectasis, which is common in the perioperative setting. Atelectasis increase the risk of postoperative pulmonary complications and result in pulmonary shunt, which is one of the two major causes of impaired oxygenation. The other cause is admixture of venous blood from poorly ventilated regions of the lungs. The investigators have developed an oxygenation test utilizing arterial blood gas analysis at different inspired fractions of oxygen, which may be used to distinguish between these two causes. This observational study aims to establish the agreement between computed tomography and the oxygenation test for estimating the extent of atelectasis.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiology (ASA) class I-II.
  • Non-abdominal day case surgery under general anesthesia.
  • Patients enrolled in study registered in ClinicalTrials with NCT ID.

Exclusion criteria

  • Arterial oxygen saturation (SpO2) <90 % with 40% Venturi mask.
  • Unstable postoperative condition needing immediate treatment.

Treatment and study plan

Primary outcomes

  1. Atelectasis area

    Time frame: 30 min after emergence from anesthesia

    Atelectasis area as studied by computed tomography

Secondary outcomes

  1. Pulmonary shunt estimated by a standardised oxygenation test

    Time frame: 30 min after emergence from anesthesia

    Pulmonary shunt estimated by a standardised oxygenation test using

Sponsors and collaborators

Lead sponsor

Region Västmanland

Other

Registry information

Official study title

A Comparison Between Two Methods for Estimating the Extent of Perioperative Atelectasis

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Nov 24, 2017
Registry last updated
Oct 12, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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