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Completed

NCT Number: NCT02017938

Establishing the Central and Peripheral Fatigue Indexes and VR Based Anti-fatigue Training Paradigm for Individuals With Parkinson Disease

Fatigue is one of the most common symptoms in individuals with Parkinson's Disease (PD). Past researches indicated that more than half of the individuals with PD demonstrated fatigue symptom. The severity of fatigue was also correlated to the quality of life in individuals with PD. Finding the contributions of the central and the peripheral factors to fatigue, building reliable fatigue indexes, and developing an effective training program for individuals with PD are very important.

The purpose of this project is to develop non-invasive method to monitor central and peripheral fatigue, to establish Virtual Reality(VR) anti-fatigue ergo cycling training paradigm, and to evaluate the long term training effect in individuals with PD.

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Key information

Conditions

Parkinson's Disease (PD) Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Fatigue Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinson Disease Parkinsonian Disorders Pathological Conditions, Signs and Symptoms Signs and Symptoms Synucleinopathies

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chang Gung University

Taoyuan, 333, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of Parkinson disease
  • Hoehn and Yahr ≦3

Exclusion criteria

  • Musculoskeletal injuries
  • Osteoporosis
  • Diabetes
  • Any peripheral or central nervous system injury or disease patients

Treatment and study plan

Virtual Reality anti-fatigue ergo cycling training (Self-made)

Procedure

To establish a Virtual Reality systems to reduce fatigue of cycling training for PD subjects.

Primary outcomes

  1. Muscle twitch force

    Time frame: baseline, 1 week

    Measure of changes in muscle twitch force by interpolation twitch technique.

  2. Muscle voluntary activity level

    Time frame: Baseline,1 week

    Measure of changes in muscle voluntary activity level by interpolation twitch technique.

  3. Heart rate/Heart rate variability

    Time frame: Baseline,1 week

    Measure of changes in Heart rate/Heart rate variability.

  4. Borg's rate of perceived exertion

    Time frame: Baseline,1 week

    Measure of changes in Borg's rate of perceived exertion.

Sponsors and collaborators

Lead sponsor

Chang Gung University

Other

Registry information

Important dates

Study start
2014
Primary completion
2015
Study completion
2016
First posted
Dec 23, 2013
Registry last updated
Apr 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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