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NCT Number: NCT07600502

Establish Whether Hyperangulated Videolaryngoscopy (HAVL) Can be Used to Facilitate Tracheal Intubation Effectively and Safely in Unselected Adult Patients; Describe the Population in Whom HAVL Fails to Facilitate Tracheal Intubation Successfully, Identifying Any Contributory Characteristics.

When patients have a general anaesthetic (go to sleep for surgery), the anaesthetist often places a small tube into their windpipe (intubation) to help them breathe. To see exactly where to put the tube, the anaesthetist uses a device called a laryngoscope.

A commonly used laryngoscope is the McGrath videolaryngoscope. It has a small camera and screen to help guide safe placement of the tube. It comes in two different shapes - one shaped in the same way laryngoscopes have been shaped for the last 80 years, and another newer design (McGrath X-blade) that matches the curve of patients' tongues better.

All different classes of videolaryngoscope have been shown to have benefits to patients; however, the best videolaryngoscope shape has yet to be determined.

The McGrath X-blade is currently recommended in patients in whom the anaesthetist thinks it might be slightly more difficult to place the tube, but some anaesthetists already prefer to use it in all their patients. This is not a new device or a new technique.

In this study, the investigators wish to explore if there is any special benefit of using it in all patients, by collecting some information when the device is used.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

St John's Hospital

Livingston, United Kingdom

Location contact

Murray Geddes

CONTACT

+44(0)1506523064

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients undergoing surgical procedures requiring tracheal intubation as part of their routine anaesthetic care
  • Patients undergoing either naso- or oro-tracheal intubation
  • Patients undergoing tracheal intubation with or without administration of neuromuscular blocking agents (e.g. those undergoing surgery where facial nerve or recurrent laryngeal nerve monitoring will be utilised)

Exclusion criteria

  • Patients <18 years of age
  • Patients in whom tracheal intubation is not required as part of their routine anaesthetic care
  • Patients in whom tracheal intubation was not planned as part of their routine anaesthetic care, but was required as a rescue technique (e.g. for failed insertion of a supraglottic airway) since appropriate patient consent will not have been obtained · Patients that are physiologically unstable (where clinical care must take priority and/or patient is unable to consent for inclusion in the study)

Treatment and study plan

Hyperangulated videolaryngoscopy

Device

Hyperangulated videolaryngoscopy using McGrath X-blade

Primary outcomes

  1. First-pass success

    Time frame: 5 minutes

    Incidence of successful tracheal intubation at the first attempt (without complications) using the McGrath-X blade

Secondary outcomes

  1. Overall incidence of tracheal intubation success

    Time frame: 5 minutes

    Overall incidence of tracheal intubation success with the McGrath-X blade without complications (maximum of 3 attempts with the device)

  2. Incidence of complications

    Time frame: 5 minutes

    Incidence of immediate airway-related complications

Study contacts

Contact information is provided by the study sponsor or research team.

Pamela Milligan

CONTACT

[email protected]

+44(0)1506523064

Patrick A Ward

CONTACT

[email protected]

+44(0)1506523064

Sponsors and collaborators

Lead sponsor

NHS Lothian

Other Gov

Collaborators

  • Medtronic

Registry information

Official study title

McGrath X-blade Study

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
May 20, 2026
Registry last updated
May 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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