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NCT Number: NCT06574802

Er:YAG Laser and Air Polishing Application in Periodontal Treatment

Periodontitis (gum disease) is an infection of the gums that can lead to tooth loss. In recent years, many types of dental lasers or other devices have been used for the non-surgical treatment of periodontal diseases. However, it remains unclear whether the combined application of laser and air polishing is effective as an adjuvant treatment for periodontitis. The purpose of this study is to compare the use of combined application of Er:YAG laser and sub-gingival air polishing powder, with the treatment of Er:YAG laser only, in periodontal diseases treatment in a Chinese population.

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Key information

Conditions

Periodontitis Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

35 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Beijing Chao Yang Hospital

Beijing, Beijing Municipality, 100020, China

Location status: Recruiting

Location contact

Xuan Zhou, Dr.

CONTACT

About this study

The study will use a split-mouth design, two quadrants (one quadrant from each jaw) were randomly allocated to either the test or control group. The quadrants in the test group received Er:YAG laser (ERL) plus sub-gingival air polishing treatment, while the quadrants in the control group received ERL only. Clinical periodontal examinations were evaluated at baseline, 3 months, 6 months, 1 year, and 2 years.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1) aged 35-65 years old, in good systemic healthy;
  • 2) clinically diagnosed with generalized stage Ⅱ or stage Ⅲ periodontitis;
  • 3) a minimum of 20 teeth

Exclusion criteria

  • 1) pregnancy or recent pregnancy plans;
  • 2) had received periodontal treatment within the previous 6 months;
  • 3) taken antibiotics within the previous 3 months;
  • 4) had diabetes;
  • 5) obvious malocclusion, history of orthodontic treatment, or a habit of mouth breathing.

Treatment and study plan

ERL + air polishing

Procedure

Er:YAG laser (ERL) plus sub-gingival air polishing treatment

ERL

Procedure

ERL treatment

Primary outcomes

  1. Changes in PD

    Time frame: at 3 months, 6 months, 1 year, and 2 years

    Changes in probing depth (PD) measured using periodontal probing

  2. Changes in CAL

    Time frame: at 3 months, 6 months, 1 year, and 2 years

    Changes in clinical attachment level (CAL) measured using periodontal probing

Secondary outcomes

  1. changes in BI

    Time frame: at 3 months, 6 months, 1 year, and 2 years

    Changes in bleeding index (BI) measured using periodontal probing

  2. PLI

    Time frame: at 3 months, 6 months, 1 year, and 2 years

    Plaque index (PLI) assessed by an examiner using a scale of 0 to 3

Study contacts

Contact information is provided by the study sponsor or research team.

Xuan Zhou, Doctor

CONTACT

[email protected]

86-10-85231344

Sponsors and collaborators

Lead sponsor

Beijing Chao Yang Hospital

Other

Registry information

Official study title

Combined Application of Er:YAG Laser and Sub-gingival Air Polishing Powder in Treatment of Periodontitis: A Split-mouth, Randomized Controlled Trial

Important dates

Study start
2024
Primary completion
2026
Study completion
2027
First posted
Aug 28, 2024
Registry last updated
Feb 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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