Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06810375

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

This clinical trial compares efficacy in postoperative pain management in thoracic surgery between erector spinae block versus liposomal bupivacaine injections.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Lung Cancers Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

The George Washington University Hospital

Washington D.C., District of Columbia, 20037, United States

Location status: Recruiting

Location contact

Eduard Shaykhinurov

CONTACT

[email protected]

202-203-8960

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Video assisted pulmonary resection, pleurodesis or decortication

Exclusion criteria

  • Allergy to local anesthetics
  • Patient undergoing bilateral surgery
  • Surgery is emergent as deemed by the principal investigator

Treatment and study plan

Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)

Drug

preoperative erector spinae block with bupivacaine (Marcaine®)

Intercostal nerve block

Drug

intraoperative intercostal nerve block with liposomal bupivacaine (Exparel®)

Primary outcomes

  1. Postoperative pain control assessment

    Time frame: Up to 48 hours postoperatively

    Study team will assess postoperative pain scores at 6, 12, 24 and 48 hours (Minimum numerical pain score of 0 and a maximum of 10)

  2. Morphine equivalent assessment

    Time frame: Up to 72 hours postoperatively

    Study team will collect information on all administered pain medications to calculate morphine equivalents

Secondary outcomes

  1. Postoperative pain control assessment

    Time frame: Up to 72 hours postoperatively

    Study team will assess postoperative pain scores at 72 hours (Minimum numerical pain score of 0 and a maximum of 10)

Study contacts

Contact information is provided by the study sponsor or research team.

Eduard Shaykhinurov, MS

CONTACT

[email protected]

2022038960

Sponsors and collaborators

Lead sponsor

George Washington University

Other

Registry information

Important dates

Study start
2025
Primary completion
2028
Study completion
2029
First posted
Feb 5, 2025
Registry last updated
Apr 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.