Erector Spinae Plane Block with Dexmedetomidine and Bupivacain Versus Dexamethasone and Bupivacain for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries

To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries

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Key information

Conditions

Analgesia, Postoperative Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age :18 years old and older. Patients undergoing open abdominal surgery.

Exclusion criteria

Patient refusal
known sensitivity or contraindication to any of study drugs
contraindications for local anesthesia
Patients with local infection at site of puncture
uncooperative patients
history of psychological disorders or chronic pain and significant liver or renal disease.

Treatment and study plan

Erector Spinae Plane Block

Procedure

dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries.

Primary outcomes

VAS score

Time frame: at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.

pain intensity using VAS score

Secondary outcomes

the time for requirement of first morphine dose

Time frame: at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.

the time for requirement of first morphine dose (hours)

Study contacts

Contact information is provided by the study sponsor or research team.

loay GAMAL loay Gamal, master

CONTACT

[email protected]

+201017675686

Sponsors and collaborators

Lead sponsor

Loay Gamal

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2026
Study completion: 2026
First posted: Oct 26, 2024
Registry last updated: Oct 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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