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Completed

NCT Number: NCT06862752

Erector Spinae Plane Block Versus Serratus Anterior Plane Block

the aim of the study compare the analgesic effect of erector spinae block and serratus anterior block in breast surgery

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Key information

Conditions

Post Operative Pain Chemically-Induced Disorders Mental Disorders Narcotic-Related Disorders Neurologic Manifestations Opioid-Related Disorders Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms Substance-Related Disorders

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Sisli etfal research and training hospital

Istanbul, 34371, Turkey (Türkiye)

About this study

Breast reduction surgery is a common cosmetic surgical procedure. Providing effective analgesia has a crucial role in reducing side effects, catalyzing postoperative recovery, and increasing patient satisfaction. Regional anesthesia techniques are generally used for postoperative analgesia to decrease opioid-related side effects. Fascial plane block has gained popularity for breast analgesia. The investigator aimed to consider the effects of ESP block or Serratus Anterior Plane block on postoperative analgesia in breast reduction surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiologists (ASA) I-II,
  • 18-65 years of age, adult,
  • female patients
  • undergoing elective breast reduction surgery

Exclusion criteria

  • Allergy to amide-type local anesthetics
  • Infection at the block injection site
  • Severe obesity (BMI > 35 kg/m2)
  • Liver or renal deficiency
  • Patients with anatomical deformities
  • Recent use of analgesic drugs
  • Patient refusal or inability to consent

Treatment and study plan

erector spine plane (ESP) block

Procedure

Bilateral ultrasound guided erector spine plane (ESP) block will be performe preoperatively at T5 level. 20 mL local anesthetics (10 mL 0.5% bupivacaine + 10 mL serum physiologic % l) will be injected deep to the erector spinae muscle.

Serratus Anterior Plane Block

Procedure

Bilateral ultrasound guided serratus plane block with 20 ml %0,25 bupivacaine at the midaxillary 5. Rib

Primary outcomes

  1. Opioid consumption

    Time frame: 24 hour

    Tramadol consumption in Patient Controlled Analgesia device postoperative 24 hours.

Secondary outcomes

  1. Pain assessed by NRS

    Time frame: 24 hour

    Post operative pain will be evaluated with Numeric rating scale (NRS) score of 0-10 (0= no pain and 10= pain) and will be recorded at 0,1,4,12,24. At hours postoperatively.

  2. Rate of opioid related side effects

    Time frame: 24 hour

    Opioid related side effects such as nause/vomiting, pruritis, bradycardia, hypotension will be evaluated at intervals up to 24 hours.

  3. Blooad loss

    Time frame: during surgery

    Peroperative and postoperative blood loss and amaoun of eritrosit suspansion

  4. Remifentanil consumption

    Time frame: during surgery

    Peroperative Remifentanil consumption

  5. Length of stay in hospital

    Time frame: 30 days

    Length of stay in hospital

Sponsors and collaborators

Lead sponsor

Sisli Hamidiye Etfal Training and Research Hospital

Other

Registry information

Official study title

Bilateral Ultrasound-Guided Erector Spinae Plane Block or Serratus Anterior Plane Block For Postoperative Analgesia in Breast Reduction Surgery: A Prospective, Randomized and Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 6, 2025
Registry last updated
Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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