Skip to main content
OpenTrials
Completed

NCT Number: NCT06710444

Erector Spinae Plane Block Versus Retrolaminar Block for Analgesia in Percutaneous Nephrolithotomy

The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postoperative Analgesia Agnosia Bites and Stings Chemically-Induced Disorders Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations PCNL Pain Pain Management Pathological Conditions, Signs and Symptoms Perceptual Disorders Poisoning Regional Anesthesia Block Signs and Symptoms Wounds and Injuries

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ahmed S.Shehab

Alexandria, 21431, Egypt

About this study

All the patients will be blinded to the intervention received in this study. All patients will receive standard general anesthesia technique with endotracheal intubation and muscle paralysis. Postoperatively, all patients will receive analgesia in the form of non-steroidal anti-inflammatory drugs and paracetamol. In case the VAS scores exceeded 4 in any group, the patients will receive rescue analgesia with 25 mg IV meperidine. In both groups, the ESPB and RLB will be performed after induction of general anesthesia using portable ultrasound device.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients scheduled for PCNL

Exclusion criteria

  • daily consumption of analgesics
  • allergy to local anesthetics
  • liver dysfunction
  • infection or previous surgery in the vertebral region.
  • patient refusal
  • pregnancy

Treatment and study plan

Ultrasound-Guided Erector Spinae Plane Block

Procedure

ESPB

ultrasound-guided retrolaminar plane block

Procedure

RLB

Primary outcomes

  1. measurement of visual analogue score

    Time frame: after the surgery average 48 hours postoperative

    measurement of visual analogue score during rest and movement. The Score range from 0-10. 0 means no pain and 10 indicates the worst pain ever

Secondary outcomes

  1. postoperative additional analgesic requirement

    Time frame: after the surgery average 48 hours postoperative

    Total cumulative analgesic requirement dose

  2. assessing the patient satisfaction by a the short assessment of patient satisfaction score (SAPS)

    Time frame: after the surgery average 48 hours postoperative

    from 0 to 28, where 0 is so dissatisfied and 28 means very satisfied

  3. Time to ambulate

    Time frame: after the surgery average 12 hours postoperative

    Time from discharge from the operating theatre to start to ambulate

  4. presence of postoperative nausea and vomiting

    Time frame: after the surgery average 48 hours postoperative

    Number of postoperative nausea and vomiting

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Official study title

Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 29, 2024
Registry last updated
May 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.