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Completed

NCT Number: NCT05406388

Erector Spinae Plane Block in Liver Transplantation Donors

Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision. Therefore adequate analgesia is important for recovery.

Erector Spinae Plane Block (ESPB) is a safe anesthesia technique used to provide postoperative analgesia. This study aimed to compare the novel ultrasound-guided ESPB technique with controls in terms of postoperative opioid consumption and postoperative pain control on donor patients.

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Key information

Conditions

Pain, Postoperative Neurologic Manifestations Pain Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istanbul Medipol University Hospital

Istanbul, 34070, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Donor patients scheduled for elective hepatectomy in liver transplantation surgery
  • ASA I-II
  • Patients who are aged between 18-65

Exclusion criteria

  • Patients who do not accept the procedure
  • Skin infection at the site of Erector Spina Plan Block area
  • Coagulation disorder or using anticoagulant drugs
  • Known local anesthetics and opioid allergy
  • Severe pulmonary and/or cardiovascular problems
  • Substance addiction or known psychiatric or mental problems
  • Chronic painkiller usage
  • Pregnancy or lactation

Treatment and study plan

Erector Spinae Plane Block

Procedure

Intravenous fentanyl patient control device 48-hour fentanyl consumption will be recorded.

Intravenous fentanyl patient control device

Procedure

Intravenous fentanyl patient control device 48-hour fentanyl consumption will be recorded.

Primary outcomes

  1. Opioid consumption

    Time frame: Change from baseline opioid consumption at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours

    The amount of fentanyl required by the patient and given by the device will be recorded for the first 48 hours.

Secondary outcomes

  1. Visual Analog Scale

    Time frame: Change from baseline pain scores at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours

    Pain of patients will be evaluated and recorded according to the Visual Analog Scale.

Sponsors and collaborators

Lead sponsor

Medipol University

Other

Registry information

Official study title

Ultrasound-guided Bilateral Erector Spinalis Plane Block on Postoperative Pain Management in Liver Transplantation Donors

Important dates

Study start
2020
Primary completion
2023
Study completion
2023
First posted
Jun 6, 2022
Registry last updated
Aug 7, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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