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OpenTrials
Active, Not Recruiting

NCT Number: NCT07479069

Erector Spinae Plane Block for Pain Control After Open Abdominal Surgery

his randomized controlled trial aims to evaluate the efficacy of the bilateral erector spinae plane (ESP) block in reducing postoperative opioid consumption in patients undergoing open abdominal surgeries under general anesthesia

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Postoperative Pain Neurologic Manifestations Open Abdominal Surgery Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anesthesia, Fatima Memorial Hospital

Lahore, Punjab Province, 54000, Pakistan

About this study

Patients undergoing abdominal surgeries experience severe postoperative pain. Conventional pain management methods, including opiates, may pose significant side effects. This study addresses the imperative need for optimizing postoperative pain management by systematically investigating the analgesic effects and complications associated with the bilateral ESP block. The study involves 46 patients allocated into two groups using a lottery method: a control group receiving standard pain control treatment, and an erector spinae block group receiving a bilateral ESP block in addition to standard pain control treatment. Pain intensity will be evaluated using a visual analogue scale (VAS) at 4, 8, 12, and 24 hours after the operation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiology (ASA) stage I-II.
  • Scheduled for abdominal surgery due to any indication.

Exclusion criteria

  • History of Diabetes
  • History of neuropathic diseases
  • History of gastrointestinal bleeding, peptic ulcer, or inflammatory bowel disease
  • History of long-term nonsteroidal anti-inflammatory
  • History of chronic opioid analgesic use
  • History of severe hepatic or renal failure

Treatment and study plan

Bilateral Erector Spinae Plane (ESP) Block

Procedure

Administered after the induction of general anesthesia and before the surgical incision. Local anesthetic (0.25% ropivacaine or 0.25% bupivacaine) will be injected for a total of 20-40 mL

Standard Postoperative Analgesia

Drug

Patients receive 1000 mg of IV paracetamol every 6 hours postoperatively. If a patient experiences a Visual Analogue Score (VAS) of more than five at any time, they receive rescue analgesia in the form of nalbuphine 4mg

Primary outcomes

  1. Postoperative Opioid Consumption

    Time frame: Within the first 24 hours after surgery

    Assessed by the percentage of patients requiring rescue opioid analgesia. The need for rescue analgesia is determined by a Visual Analogue Score (VAS) greater than five

Sponsors and collaborators

Lead sponsor

Fatima Memorial Hospital

Other

Registry information

Official study title

Effect of Bilateral Erector Spinae Plane Block on Postoperative Opioid Consumption in Open Abdominal Surgeries Under General Anaesthesia

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 18, 2026
Registry last updated
Mar 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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