Dentoplex
Bielsko-Biala, 43-300, Poland
NCT Number: NCT07064304
Abstract: Introduction: The deepithelialized free gingival graft (DGG) technique provides high-quality connective tissue grafts (CTGs) with predictable outcomes for recession cov-erage. This study evaluates a novel method of free gingival graft (FGG) deepithelialization using an Er,Cr:YSGG laser (LDEE) for treating multiple gingival recessions. Methods: A split-mouth study was conducted on 46 (n=46) recessions in 9 patients (23 per test and control group). Sites were randomized. Full-thickness palatal grafts were harvested with a scalpel. In the test group (LDEE), deepithelialization was performed extraorally using an Er,Cr:YSGG laser (2780 nm; 2.5 W, 83.3 mJ, 30 Hz, 600 µm tip). In the control group (DEE), a 15c scalpel was used. All CTGs were applied using the modified coronally advanced tunnel (TUN) technique. Clinical parameters-recession depth (RD), keratinized tissue width (KT), gingival thickness (GT), pocket depth (PD), clinical attachment loss (CAL), pink esthetic score (PES), approximal plaque index (API), mean root coverage (MRC), and complete root coverage (CRC)-were assessed at baseline (T0), 3 months (T1), and 6 months (T2). Results: Both LDEE and DEE groups showed significant improvements in RD, KT, GT, PD, and CAL over time (p < 0.001). At T1 and T2, KT was significantly higher in the LDEE group (T1: 3.73±0.72 mm; T2: 3.98±0.76 mm) compared to the DEE group (T1: 3.21±0.61 mm; T2: 3.44±0.74 mm; p < 0.05). Other parameters (RD, GT, PD, CAL) showed no statistically significant intergroup differences at any time point (p > 0.05). After 6 months, MRC was 95% and CRC 82.6% for LDEE, compared to 94.8% and 82.6% for DEE (p > 0.05). PES scores were similar between groups at all time points (p > 0.05). Conclusion: Both laser- and scalpel-deepithelialized grafts effectively treated gingival recessions. LDEE combined with TUN resulted in significantly greater KT width compared to DEE + TUN.
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Notify Me18 year–70 year
All sexes
Interventional
Not applicable
Bielsko-Biala, 43-300, Poland
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Extraoral deepithelialization of harvested free gingival graft using Er,Cr:YSGG laser (2780 nm, 2.5 W, 83.3 mJ, 30 Hz, 600 μm tip) before placement in gingival recession treatment.
Extraoral deepithelialization of harvested free gingival graft using a 15c surgical scalpel blade before placement in gingival recession treatment.
Time frame: Baseline, 3 months, and 6 months postoperatively
Measurement of gingival recession depth in millimeters to evaluate soft tissue response to treatment.
Unit of Measure: mm
Time frame: Baseline, 3 months, and 6 months postoperatively
Measurement of the width of keratinized gingiva in millimeters from the mucogingival junction to the free gingival margin.
Unit of Measure: mm
Time frame: Baseline, 3 months, and 6 months postoperatively
Assessment of gingival tissue thickness using a standardized probe. Unit of Measure: mm
Time frame: Baseline, 3 months, and 6 months postoperatively
Probing depth measured from the gingival margin to the base of the periodontal pocket.
Unit of Measure: mm
Time frame: Baseline, 3 months, and 6 months postoperatively
Measurement of the distance from the cementoenamel junction to the base of the periodontal pocket.
Unit of Measure: mm
Time frame: Baseline, 3 months, and 6 months postoperatively
Percentage of interdental spaces with visible plaque, calculated to assess oral hygiene status. A lower percentage indicates better plaque control.
Unit of Measure: percentage (%)
Time frame: 6 months postoperatively
Average percentage of root surface covered by soft tissue following treatment, calculated across all treated sites.
Unit of Measure: percentage (%)
Time frame: 6 months postoperatively
Proportion of treated sites that achieved 100% root coverage postoperatively. Unit of Measure: percentage (%)
Time frame: Immediately postoperatively
Microscopic assessment of grafts treated with Er,Cr:YSGG laser to evaluate the quality of deepithelialization and potential thermal damage. Parameters included the presence of a clear boundary between epithelium and connective tissue, absence of carbonization or necrosis, and preservation of tissue architecture.
Wroclaw Medical University
Other
Clinical Efficacy of Er,Cr:YSGG Laser for Deepithelialization of Free Gingival Grafts in Gingival Recession Treatment: A Randomized, Split-Mouth Clinical Trial
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