Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07451093

Epileptiform Potential of Fully Immersive Virtual Reality

The goal of this interventional study is to determine if the use of virtual reality headsets results in an increased risk of seizure in adolescent and adult individuals with epilepsy. The main question it aims to answer are:

- does use of virtual reality headsets with hand controllers result in a higher risk of seizure compared to use of virtual reality headsets without hand controllers Participants will be asked to wear a virtual reality headset during continuous video EEG recording and EEG with be evaluated during three phases: with display turned off, with display turned on without hand controllers, and with display turned on with hand controllers.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Epilepsy Brain Diseases Central Nervous System Diseases Epilepsy, Reflex Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Seizure Seizures Signs and Symptoms

Age range

13 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States

Location contact

Jared E Quast, MD

CONTACT

[email protected]

6033505104

Jared E Quast, MD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • subjects with known or suspected diagnosis of epilepsy with interictal epileptiform discharges seen during current or prior EEG recording
  • Age greater than or equal to 13 years

Exclusion criteria

  • Age less than 13 years (infants, children)
  • Pregnancy
  • Incarceration
  • Moderate-severe cognitive impairment

Treatment and study plan

Virtual Reality Headset, display off

Other

15 minutes of EEG recording with VR headset worn, display turned off. This will act as a baseline for intervention 2 and 3

Virtual Reality Headset, Display only

Other

15 minutes of EEG recording with VR headset worn, display turned on without access to hand controls.

Virtual Reality Headset, Display and Hand Control

Other

15 minutes of EEG recording with VR headset worn, display turned on with access to hand controls

Primary outcomes

  1. Change in prevalence of interictal epileptiform discharges

    Time frame: Three sessions, 15 minutes each

    Interictal epileptiform discharges are counted by two epilepsy trained neurologists. Number of discharges seen are compared between each intervention.

Other outcomes

  1. Seizure

    Time frame: 3 trials, 15 minutes each

    Detection of a clinical or electrographic seizure event occurring with any intervention

Study contacts

Contact information is provided by the study sponsor or research team.

Jared E Quast, MD

CONTACT

[email protected]

6033505104

Sponsors and collaborators

Lead sponsor

Dartmouth-Hitchcock Medical Center

Other

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Mar 5, 2026
Registry last updated
May 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.