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Completed

NCT Number: NCT03860467

Epileptic Seizures in Intensive Care Units

This retrospective observational cohort study is to assess and analyze clinical, electroencephalographic, laboratory, comorbidity, and treatment characteristics of Intensive care unit (ICU)-patients with epileptic seizures and to subsequently compare their characteristics with ICU-patients with status epilepticus (SE).

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Key information

Conditions

Epileptic Seizure Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Seizures Signs and Symptoms Status Epilepticus

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Clinic for Intensive Care Medicine, University Hospital Basel

Basel, 4031, Switzerland

About this study

The aim of this retrospective observational cohort study is to get further insight into adult patients with epileptic seizures in ICUs in an academic tertiary medical care center regarding frequency, clinical and electroencephalogram (EEG) characteristics, treatment, course and outcome. This data could help understanding the epidemiology (including risk factors, influence of EEG), and to guide management and improve outcomes of affected patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • admitted to the ICU at the University Hospital Basel
  • suffered from one or more epileptic seizures (detected clinically and/or by EEG) during their ICU-stay

Exclusion criteria

  • patients with epileptic seizures transforming into Status epilepticus (SE)

Treatment and study plan

collection of patient data

Other

Patient data will be collected using the in-house digital patient record systems and the local digital electroencephalogram (EEG)-database

Primary outcomes

  1. Frequency of epileptic seizures

    Time frame: between 01.01.2005 and 19.12.2018

    Frequency of all epileptic seizures in the ICU

Secondary outcomes

  1. Number of epileptic seizures captured by EEG

    Time frame: between 01.01.2005 and 19.12.2018

    Number of epileptic seizures captured by EEG without overt clinical seizure presentation in the ICU

  2. Number of epileptic seizures diagnosed on the basis of clinical symptoms alone

    Time frame: between 01.01.2005 and 19.12.2018

    Number of epileptic seizures diagnosed on the basis of clinical symptoms alone in the ICU

  3. Length of epileptic seizure (time)

    Time frame: between 01.01.2005 and 19.12.2018

    Duration of epileptic seizure

  4. Semiological feature of epileptic seizure (i.e. seizure types)

    Time frame: between 01.01.2005 and 19.12.2018

    Semiological feature of epileptic seizure (i.e. seizure types) emerging in ICU-patients

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Registry information

Important dates

Study start
2019
Primary completion
2022
Study completion
2022
First posted
Mar 4, 2019
Registry last updated
Jun 2, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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