Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07026591

Epilepsy and Driving

Epilepsy can lead to cognitive impairments, particularly in attention, which may affect daily activities such as driving. Driving plays a key role in maintaining autonomy and is essential for the social and professional integration of people with epilepsy. Therefore, assessing fitness to drive is a major issue for individuals with epilepsy.

French legislation governing driving for people with epilepsy clearly outlines the periods during which a person is not permitted to drive. However, the means or methods for evaluating driving fitness in these individuals are not well defined. Currently, assessment is based more on a medical consultation than on a comprehensive evaluation of driving ability.

Using a driving simulator in combination with an EEG could be a valuable approach to better assess the impact of epilepsy-related cognitive impairments on driving performance.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Epilepsy Brain Diseases Central Nervous System Diseases Nervous System Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Institut La Teppe

Tain-l'Hermitage, 26600, France

Location status: Recruiting

Location contact

Cécile Sabourdy, Dr

CONTACT

[email protected]

+33475075959

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 18 and 65 years
  • Holder of a category B driving license
  • Active driver: drives at least once a month
  • No medical condition contraindicating driving, except for epilepsy
  • Provides explicit consent to participate in the study
  • Affiliated with or a beneficiary of a social security scheme

Exclusion criteria

  • Subject to legal protection (guardianship and curatorship are accepted for individuals with epilepsy, as this population represents a significant proportion of our institution's patients)
  • Pregnant or breastfeeding women
  • Known cybersickness (virtual reality or simulator sickness)

Treatment and study plan

Primary outcomes

  1. Speed

    Time frame: Day 0

    Mean speed during the simulated driving task

  2. Phasic alertness

    Time frame: Day 0

    Phasic alertness on neuropsychological test (TAP)

  3. Lane position

    Time frame: Day 0

    Mean lane position during the simulated driving task

  4. Braking time

    Time frame: Day 0

    Mean braking time during the simulated driving task

  5. Information processing time

    Time frame: Day 0

    Mean information processing time during the simulated driving task

  6. Sustained attention

    Time frame: Day 0

    Sustained attention on neuropsychological test (TAP)

  7. Divided attention

    Time frame: Day 0

    Divided attention on neuropsychological test (TAP)

  8. Visual scanning

    Time frame: Day 0

    Visual scanning on neuropsychological test (TAP)

Study contacts

Contact information is provided by the study sponsor or research team.

Amelie Yavchitz

CONTACT

[email protected]

+33 1 48 03 64 54

Sponsors and collaborators

Lead sponsor

Fondation Ophtalmologique Adolphe de Rothschild

Network

Registry information

Acronym: EPICO

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Jun 18, 2025
Registry last updated
Dec 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.