Epigenetic Changes in Head and Neck Cancer

With this study, the investigators will investigate the epigenetic changes, which may contribute to the development of head and neck squamous cell carcinomas.

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Key information

Conditions

Head and Neck Cancer Carcinoma Carcinoma, Squamous Cell Head and Neck Neoplasms Head and Neck Squamous Cell Carcinoma Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Neoplasms, Squamous Cell Squamous Cell Carcinoma Squamous Cell Carcinoma of Head and Neck

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Otolaryngology - Head and Neck Surgery

Aalborg, 9000, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Cancer group:

Inclusion criteria

Written informed consent
Histologically confirmed oral squamous cell carcinoma

Exclusion criteria

History of cancer
Uncontrolled comorbidity

Control group:

Inclusion criteria

Written informed consent
Normal buccal mucosal surface.
Normal ENT-examination

Exclusion criteria

History of cancer
Uncontrolled comorbidity

Treatment and study plan

Primary outcomes

Differences in epigenetic changes

Time frame: 6 months

Differences between tumor- and healthy group

Sponsors and collaborators

Lead sponsor

Aalborg University Hospital

Other

Registry information

Official study title

Biomarkers in Head and Neck Cancer - Epigenetic Changes and Hypermethylation of Promoter-regions

Important dates

Study start: 2020
Primary completion: 2021
Study completion: 2021
First posted: Feb 7, 2020
Registry last updated: Jul 21, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed