Skip to main content
OpenTrials
Completed

NCT Number: NCT03638401

Epidural vs. Wound Catheter Following Liver Resection

Good postoperative pain control after any major surgery allows early mobilization, minimises postoperative complications and reduces patient distress. Multiple different methods of delivering analgesia have been described.

This study aims to compare postoperative pain control between patients with epidural analgesia versus the combination of continuous infiltration of local anaesthetic with wound catheters, TAP block and IV PCA with opiate analgesia following open liver resection. The investigators expect that pain control will be similar between the two groups but that the utilization of wound catheters will confer benefit due to the lack of systemic side effects associated with epidural analgesia

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Transplant Surgery

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Leeds Teaching Hospitals NHS Trust

Leeds, LS1 3HE,, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All adult patients scheduled to undergo an open liver resection at this hospital will be eligible to participate.

Exclusion criteria

  • Patients with a contraindication to either epidural or wound catheter
  • Inability to give written, informed consent
  • Aged less than 18 years old
  • Liver resection combined with a secondary surgical procedure
  • Body mass index of <18 or >40
  • Pregnancy or lactation
  • A history of chronic pain requiring regular opioid analgesia
  • Prisoners

Treatment and study plan

This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

Procedure

This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

Primary outcomes

  1. The length of hospital stay following open liver resection

    Time frame: 6 months (or length of the study)

Sponsors and collaborators

Lead sponsor

The Leeds Teaching Hospitals NHS Trust

Other

Registry information

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Aug 20, 2018
Registry last updated
Aug 20, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.