Skip to main content
OpenTrials
Completed

NCT Number: NCT02518386

Epidemiology of Acute Self-poisoning in Emergency Services in France

Acute self poisoning is a leading cause of suicide attempts and leads to frequent emergency department visits. However, the exact epidemiology of acute self poisoning is not known. The description of the clinical pathway and the characteristics of patients with acute self poisoning could lead to an improvement in emergency care.

The Investigators will conduct a 48h observational study in emergency services in France. Investigators primary objective is to gathered epidemiological clinical and treatment data during emergency dispatch, prehospital care and inhospital emergency care.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Suicide Attempts Behavior Behavioral Symptoms Disease Attributes Emergencies Pathologic Processes Pathological Conditions, Signs and Symptoms Self-Injurious Behavior Suicide Suicide, Attempted

Sex eligibility

All sexes

Study type

Observational

About this study

Acute self poisoned patients will be prospectively and anonymously recruited by emergency physicians in charge during two days. Acute self poisoning is define as follow: intentional medicine intake in the 24h hours before emergency department admission.

Epidemiological, clinical, toxicological and treatment data will be gathered. Outcome of patient will be prospectively assessed at 30days.

All data will be transmitted to the principal investigators. Then, 20% of the data will be monitored by an independent committee.

Exhaustivity will be retrospectively assessed by the number of inclusions in 10 emergency centers divided by the total number of possible inclusions in these centers.

Finally, an independent statistician will be in charge of the analysis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • acute self poisoning defined as the intentional intake (oral, nasal, injection etc.) of medicines during the 24h before first medical contact

Exclusion criteria

  • cardiac arrest at first medical contact (dispatch or physician)
  • acute self poisoning without any medication intake
  • non intentional poisoning

Treatment and study plan

No intervention

Other

No intervention is planned

Primary outcomes

  1. Percentage of each drug class

    Time frame: 48h

Secondary outcomes

  1. odds ratio of drug classes according to sexe and age

    Time frame: 48h

  2. number of participants with poisoning incident

    Time frame: 48h

  3. prehospital and inhospital mortality

    Time frame: 30 days

  4. percentage of each antidotal treatment

    Time frame: 48h

  5. mobile intensive care unit (percentage) dispatch

    Time frame: 30 days

  6. Age according to drug classes ingestion

    Time frame: 48h

    Median age compared according drug classes ingestion

  7. Gender according to drug classes ingestion

    Time frame: 48h

    Pourcentage of gender compared according drug classes ingestion

  8. Time (median) of admission according to drug classes ingestion

    Time frame: 48h

  9. Time (median) of admission according unit of admission

    Time frame: 48h

  10. Mortality according to drug class ingestion

    Time frame: 30 days

  11. ICU admission according to drug class ingestion

    Time frame: 30 days

  12. icu admission (percentage)

    Time frame: 48h

  13. percentage of errors according to the Grenoble clinical decision rule

    Time frame: 30 days

  14. multivariate analysis to describe factors associated with ICU admission

    Time frame: 30 days

  15. multivariate analysis to describe factors associated with mobile intensive care unit dispatch

    Time frame: 30 days

Sponsors and collaborators

Lead sponsor

University Hospital, Grenoble

Other

Collaborators

  • French Society of Emergency Medicine

Registry information

Official study title

Evaluation of the Epidemiology and the Take Load of Voluntary Drug Intoxications by the Emergency Structures in France

Acronym: EpiTox

Important dates

Study start
2015
Primary completion
2015
Study completion
2016
First posted
Aug 7, 2015
Registry last updated
Apr 17, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.