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Completed

NCT Number: NCT04451707

Epidemiology Non-cholera Vibrio Infections

The purpose of this study is to identify the epidemiological and clinical characteristics of patients diagnosed with non-cholera Vibrio infection in Western France from 2000 to 2019.

Completed

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Key information

Conditions

Vibrio Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Negative Bacterial Infections Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Angers, Angers, France

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About this study

Vibrios are gram-negative, ubiquitous bacteria of the marine flora and are found particularly in warm waters. For example, the incidence is high in Florida and Vibrio infections are now reportable in the United States. Different species of Vibrio are described. A distinction is made between choleric vibrios belonging to serogroups O1 and O139, responsible for cholera epidemics, and non-choleric vibrios. Our study will focus on non-cholera vibrios. Vibrio infections can occur by eating contaminated raw seafood or by exposure of a wound to the marine environment. They occur mainly during the hot summer months. This can be explained on the one hand by higher water temperature and on the other hand by increased beach use. With global warming, it is possible that Vibrio infections may increase in number and location.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • non-cholera Vibrio infection

Exclusion criteria

  • vibriosis to Vibrio cholerae O1 and O139

Treatment and study plan

non-cholera Vibrio infection

Other

Epidemiology of patients diagnosed with non-cholera Vibrio infection

Primary outcomes

  1. Number of Participants With Diagnosed Non-cholerae or Non-O1/O139 Vibrio Infection

    Time frame: Up to 20 years, from 2000-2019

    A non-cholerae or non-O1/O139 Vibrio infection was defined by a biological sample (blood, superficial sample, deep sample, and ear sample) positive to a Vibrio species other than Vibrio cholerae O1-O139.

Secondary outcomes

  1. Number of Patients Per Clinical History

    Time frame: at inclusion

    Clinical history: diabetes, heart failure, hepatopathy, neoplasia, alcohol use disorder, Immunosuppressive drug, Pre-existing wound, Digestive surgery, Hemopathy, Kidney Disease

  2. Number of Participants Associated With Environmental Factors

    Time frame: at inclusion

    environmental factors : seafood consumption, bathing/water activity, Injury in the aquatic environment, Walk to the beach, Handling of seafood products, returning from a trip abroad

  3. Number of Participants Per Identified Species

    Time frame: at inclusion

    Species: Vibrio alginolyticus, Vibrio cholerae Non-O1/Non-O139 Non toxinogenic, Vibrio parahaemolyticus, Vibrio vulnificus, Vibrio sp or other

  4. Number of Participants by Month of the Years

    Time frame: at inclusion

  5. Number of Participants Treated by Antibiotics

    Time frame: through study completion, an average of 1 month

  6. Number of Participants Per Outcome

    Time frame: through study completion, an average of 1 month

    outcome :cure, cure with amputation, and deceased due to the infection

Sponsors and collaborators

Lead sponsor

Groupe Hospitalier de la Rochelle Ré Aunis

Other

Registry information

Official study title

Multicentre Retrospective Study on the Clinical and Epidemiological Characteristics and Therapeutic Management of Non-cholera Vibrio Infections

Acronym: INFECTIVE

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Jun 30, 2020
Registry last updated
Oct 31, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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