Enterobius Vermicularis Infestation of the Appendix

This study identifies the incidence of appendiceal Enterobius vermicularis (E.v) infestation in all the patients undergoing appendectomy and evaluates the relationship between E.v infestation of the appendix and the acute appendicitis.

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Key information

Conditions

Parasitic Disease Infections Parasitic Diseases

Age range

4 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Abdulkarim Hasan

Baljurashi, Saudi Arabia

About this study

All the patients undergoing appendectomy surgical procedure for clinical picture of acute appendicitis in 3-years period at our referral hospital were evaluated to pick up the Enterobius vermicularis infestation of the appendix. These cases were evaluated for clinico-laboratory characterization to define the incidence in our country and the relationship between the E.v and initiation of the the inflammatory process to study the possibility of limitation of surgical intervention in acute abdomen conditions.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All routine examined appendectomy specimens

Exclusion criteria

Cases with clinical suspicion of tumor Cases attached to the colectomy specimens

Treatment and study plan

Pathology examination

Diagnostic Test

Gross and microscopic evaluation

Primary outcomes

Association between acute inflammation and Enterobius vermicularis infestation

Time frame: 3 years

All the studied Enterobius vermicularis cases will be evaluated microscopically to record the count of acute inflammatory cells per millimeter (mm) and per High Power Field (HPF) using the microscope scale measurement. This count will be compared with the inflamed appendectomy specimens without Enterobius infestation to assess the hypothesis of the association between the Enterobius infestation and the acute appendicitis. Also special stain (congo red) will be implicated in some indicated cases to detect eosinophils, eosinophils will be positively staines (orange color stain means positive) if the stain is faint that means negative and the cell is not eosinophil
Incidence of Appendiceal Enterobius vermicularis

Time frame: 3 years

An incidence of Enterobius infestation will be assessed by studying all the received specimens during a 3 years-period using formatting a master sheet and processing in Excel program

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Enterobius Vermicularis in Appendectomy Specimens; Clinicopathological Assessment

Important dates

Study start: 2017
Primary completion: 2020
Study completion: 2020
First posted: Oct 6, 2020
Registry last updated: Oct 6, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed