Skip to main content
OpenTrials
Completed

NCT Number: NCT03833505

Enterobius Vermicularis and Bruxism in Children

Background. Bruxism is an involuntary, non-functional activity of the masticatory system, and is frequently seen in childhood. Bruxism has many aetiologies, like malocclusion, psychological factors, allergies and gastrointestinal disorders.

Aim. To investigate the relationship between Enterobius vermicularis infection and bruxism in children.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Bruxism, Sleep Bruxism Mental Disorders Nervous System Diseases Parasomnias Sleep Bruxism Sleep Wake Disorders Stomatognathic Diseases Tooth Diseases

Age range

3 year–10 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Adnan Menderes University, Faculty of Dentistry, Department of Pediatric Dentistry

Aydin, Turkey (Türkiye)

About this study

Bruxism has many aetiologies, like occlusal interferences, malocclusion, malnutrition, psychological factors, allergies and gastrointestinal disorders. Among these gastrointestinal disorders, are various intestinal parasitic infections.

Given the controversy surrounding the potential association between bruxism and intestinal parasitic infestations, both important health issues, this study sought to evaluate the relationship between E. vermicularis infection and bruxism in E. vermicularis-positive and E. vermicularis-negative 3-10-year-olds children with bruxism.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Teeth-grinding at least once a week in the last 3 months before recruitment according to the criteria established by the American Academy of Sleep Medicine (AASM)
  • Angle class I occlusion
  • Mesial step occlusion according to flush terminal plane.

Exclusion criteria

  • Treated with anti-helminthic drugs in the last 2 months before recruitment
  • Drugs used that could affect the central nervous system and prevent sleep (sedatives, anti-depressants, neuroleptics, anti-muscarinics, selective serotonin re-uptake inhibitors)
  • Sleep disorders (snoring, insomnia, obstructive sleep apnoea, restless leg syndrome, sleep-related epilepsy)
  • Psychiatric or neurological disorders
  • Upper respiratory system obstruction (last 15 days),
  • Any systemic disease;
  • Teeth erosion due to internal (reflux) or external (acidic drinks) factors
  • Dermatological problems, associated with the use of BiteStrip (Up2dent, Inc., Pulheim, Germany);
  • Unsuitable skin structure;
  • Previously diagnosed and treated for bruxism;
  • Angle class II or class III occlusion

Treatment and study plan

Bitestrip

Other

The parents of the patients were asked to complete a survey that included questions about the demographic data, medical history of the patient, clinical findings of E. For diagnosis of sleep bruxism, a single-use BiteStrip® device (Up2dent, Inc.), including an electromyographic electrode, small display screen and lithium cell, was used to record the increased electromyographic activity of the masticatory muscles during sleep and bruxism, other harmful oral habits, family life and habits.

Primary outcomes

  1. Survey

    Time frame: 24.03.2017-20.05.2018

    The parents of the patients were asked to complete a survey that included questions about the demographic data, medical history of the patient, clinical findings of E. vermicularis and bruxism, other harmful oral habits, family life and habits.

Secondary outcomes

  1. Oral examination

    Time frame: 24.03.2017-20.05.2018

    The patients who had a teeth-grinding habit were invited to, our clinic for clinical evaluation of bruxism. Patients were examined under a reflector light with inspection, palpation and mirror-sond. The extraoral examination evaluated mandibular asymmetry, joint sounds, deviation/deflection during opening/closing actions, sensitivity to palpation of masticatory muscles and pain/tenderness, sensitivity to palpation of the temporomandibular joint and masseter muscle hypertrophy10. The intraoral examination assessed the presence of wear facets on the teeth, according to a modification of the method by Johansson. The assessed teeth included primary incisors, canines and molars, permanent incisors and lower first molars. Scores were calculated as follows: 0 = no wear (none); 1 = enamel wear only (mild); 2 = enamel and dentin wear (moderate); 3 = significant loss of tooth structure (severe).

Other outcomes

  1. BiteStrip

    Time frame: 24.03.2017-20.05.2018

    For diagnosis of sleep bruxism, a single-use BiteStrip® device (Up2dent, Inc.), including an electromyographic electrode, small display screen and lithium cell, was used to record the increased electromyographic activity of the masticatory muscles during sleep.

Sponsors and collaborators

Lead sponsor

Aydin Adnan Menderes University

Other

Registry information

Official study title

Evaluation of Relationship Between Enterobius Vermicularis Infection and Bruxism in Children

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Feb 7, 2019
Registry last updated
Feb 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.