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OpenTrials
Completed

NCT Number: NCT02590120

Enteral Nutrition and Amino Acid Absorption

The purpose of this study is to evaluate amino acid absorption with two different type of proteins.

Completed

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Key information

Conditions

Malabsorption Digestive System Diseases Gastrointestinal Diseases Intestinal Diseases Malabsorption Syndromes Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU de Lille

Lille, 59037, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient with gastrointestinal disorder : citrulline plasma concentration < 20 µmol/L and/or xylose plasma concentration < 1,7 mmol/L
  • Patient under enteral nutrition at home
  • Patient already receiving 1 L by day

Exclusion criteria

  • Obese patient BMI > 30
  • Diabetes
  • Renal or liver failure
  • Glucocorticoids treatment

Treatment and study plan

Enteral Nutrition

Dietary Supplement

Primary outcomes

  1. Amino acid absorption profile

    Time frame: 48 hours

    Area under the curve of amino acid plasma concentration

Secondary outcomes

  1. Tolerance

    Time frame: 48 hours

    Description and occurence of adverse events

  2. Nutritional status

    Time frame: 48 hours

    Retinol Binding Protein and Transthyretin dosage

  3. Essentials amino acid absorption

    Time frame: 48 hours

    Area under the curve of plasma concentration

  4. Insulinemia evolution

    Time frame: 48 hours

    Insulinemia dosage

  5. Link between amino acid and insuline

    Time frame: 48 hours

    Correlation coefficient

Sponsors and collaborators

Lead sponsor

Société des Produits Nestlé (SPN)

Industry

Registry information

Official study title

Comparaison du Profil d'Absorption Des Acides aminés Entre Une Nutrition entérale Semi-élémentaire et Une Nutrition entérale polymérique

Acronym: PEPS

Important dates

Study start
2015
Primary completion
2021
Study completion
2021
First posted
Oct 28, 2015
Registry last updated
Apr 15, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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