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NCT Number: NCT06890559

Enhancing Vaccination Uptake Through Points Redemption Based Financial Incentives and Digital Platforms: an Open-label Cluster Randomized Controlled Trial Utilizing Community Mobilization and Empowerment Strategies

The overall goal is to develop and optimize a health digital platform and points redemption-based financial incentive interventions for the promotion of non-National Immunization Program (non-NIP) vaccination uptake and related preventative behaviors in China, and formulate a low-cost, labor-saving and replicable pattern. The primary objective is to develop and optimize a digital platform-based point-redemption and financial incentive system and evaluate the effectiveness of the interventions for improving non-NIP vaccines coverage and related preventive behaviors.The main questions it aims to answer are:

H1: Participants allocated to the intervention group will demonstrate a 3% increase in vaccine doses of targeted non-NIP vaccines, including HPV vaccines, influenza vaccines, pneumonia vaccines, rotavirus vaccines, varicella vaccines, and haemophilus Influenza Type B polysaccharide conjugate (Hib) vaccines, compared to those in the control group at the 12-month follow-up.

H2: Participants allocated to the intervention group will exhibit a 5% increase in the prevalence of related preventive behaviors compared to those in the control group at the 12-month follow-up.

Researchers will compare the financial incentive intervention to the routine activities to see if the intervention works to improve the vacciantion rate of non-NIP vaccines.

Participants will:

1. Participants can automatically input their health behaviors through the digital platform, and the back-end will verify the information with data provided by the township hospitals or community health centers. 2. A QR code will be implemented at each township hospital or community health center. Participants will scan the QR code after completing vaccination or other related preventive behaviors. The digital platform will automatically record points for each completed behavior. 3. Use accumulated points to redeem gifts on the system, including household goods, electronic products, and free or discounted health services.

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Key information

Conditions

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Do not move from the original research and implementation site within the next year;
  • Voluntarily participate in the study and sign the informed consent;
  • No mental disorder or cognitive impairment, able to understand and cooperate with research requirements.

Exclusion criteria

  • Have contraindications related to vaccination;
  • The state of the body during the intervention period is not suitable for vaccination.

Treatment and study plan

financial incentive intervention based on a digital platform

Behavioral

The intervention will span a duration of 12 months. All residents in the 8 intervention subdistricts/townships are available for participation; each participant household needs to register a household account on the digital platform. Each family member who completes targeted vaccine uptake or related health behaviors can earn points through two point-recording routes. Reward points will be accumulated on a household basis to encourage family members' engagement. Points can be redeemed for gifts on the digital platform and are only valid once.

Primary outcomes

  1. The number of targeted non-NIP vaccine doses per 1,000 person-years

    Time frame: one year

    The primary outcome of interest is the number of targeted non-NIP vaccine doses per 1,000 person-years. The targeted vaccines in this study include HPV vaccines, influenza vaccines and pneumonia vaccines.

Secondary outcomes

  1. Number of cervical cancer screenings, medical checkups for the elderly, and check-ups for children during the intervention period

    Time frame: one year

    Preventive behaviors related to vaccination, such as cervical cancer screening, medical checkups for the elderly,and check-ups for children during the intervention period. We will count the total number of occurrences through the participant's medical records and the number of times these behaviours are self-reported through the digital platform.

Sponsors and collaborators

Lead sponsor

Bo Yan

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Mar 24, 2025
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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