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OpenTrials
Completed

NCT Number: NCT07018232

Enhancing Timely Access to Medication Changes: The Role of Pharmacists in Overcoming Transitions of Care Challenges

Objective: Among patients discharged from the hospital with changes in maintenance prescription medication, how does experiencing a medication access gap compared to a no medication access gap impact the time to first unplanned healthcare encounter?

This is a retrospective, cohort study conducted at two hospital sites in rural Pennsylvania and New York State using encounter data from the electronic health record to analyze any patient discharged with medication changes from June 1, 2023 to May 31, 2024.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Robert Packer Hospital

Sayre, Pennsylvania, 18840, United States

About this study

Background: Transitions of care are high-risk periods marked by frequent medication-related problems with up to 80% of discharged patients and 98% of older adults experiencing discrepancies in their medication regimens. These gaps, often due to delayed prescription refills or poor care coordination, contribute to unplanned healthcare encounters, increased costs, and strain on providers. Pharmacists can mitigate these risks by improving medication access and continuity.

Objective: Among patients discharged from the hospital with changes in maintenance prescription medication, how does experiencing a medication access gap compared to a no medication access gap impact the time to first unplanned healthcare encounter?

This is a retrospective, cohort study conducted at two hospital sites in rural Pennsylvania and New York State using encounter data from the electronic health record to analyze any patient discharged with medication changes from June 1, 2023 to May 31, 2024.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 years and older
  • Have a Guthrie primary care provider
  • Discharged from the hospital to home or self-care (routine)
  • Had a medication change on discharge based on a discharge summary and/or after visit summary (AVS) containing "start taking these medications", "continue these medications which have changed", and/or "stop taking these previous medications".

Exclusion criteria

  • Age less than 18 years of age
  • Do not have a Guthrie primary care provider
  • Discharged from the hospital to anywhere besides home or self-care (routine) such as to rehabilitation, long-term care, left against medical advice, or transferred to another type of healthcare institution
  • prescriptions on discharge that lack e-prescribing class
  • prescriptions on discharge for day supplies less than 28 days
  • prescriptions on discharge for day supplies greater than 45 days
  • prescriptions on discharge with 1 or more refills provided
  • prescriptions on discharge for as needed medications
  • prescriptions on discharge for anti-infective agent
  • prescriptions on discharge for short-term steroids
  • prescriptions on discharge for nausea medication
  • prescriptions on discharge for bowel regimen medication
  • prescriptions on discharge for diabetic or medical supplies
  • prescriptions on discharge for topical medications
  • prescriptions on discharge for cough suppressants,
  • prescriptions on discharge for vitamins and supplements
  • prescriptions on discharge for medications that can be purchased over the counter

Treatment and study plan

Unplanned healthcare encounter

Behavioral

Patient needing to connect with healthcare to fill a medication gap

Primary outcomes

  1. Number of days to first unplanned healthcare encounter post-discharge

    Time frame: 90 days after discharge

    The study will compare number of days between patients who had a medication gap and patients who had no medication gap

Secondary outcomes

  1. Number of days that a patient is without a prescribed medication post-discharge

    Time frame: 90 days after discharge

    The study will compare the number of days patients are without a prescribed medication after hospital discharge, for the two groups (1 patients who had a medication gap and 2 patients who had no medication gap).

  2. Describe the types of drug-related problems and/or medication access barriers between the two groups

    Time frame: 90 days after discharge

    The study will compare the types of drug-related problems and medication access barriers between the two groups (1 patients who had a medication gap and 2 patients who had no medication gap).

Sponsors and collaborators

Lead sponsor

The Guthrie Clinic

Other

Registry information

Official study title

Enhancing Timely Access to Medication Changes: The Role of Ambulatory Care Pharmacists in Overcoming Transitions of Care Challenges

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 12, 2025
Registry last updated
Jun 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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