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Active, Not Recruiting

NCT Number: NCT02118649

Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

Participants will play a computer game that is controlled by their gaze patterns and designed to direct attention their attention to specific on-screen targets. Visual attention to targets will be rewarded. Both visual behavior and brain response will be recorded during game play.

It is hypothesized that that, over the course of the game, relative to baseline, participants will show (a) increased looking to targets, (b) decreased response time to targets, and (c) enhanced, more efficient neural response to visual cues. It is hypothesized that clinical variability will associate with visual attention and brain response.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Neurodevelopmental Disorders Mental Disorders

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Yale Child Study Center

New Haven, Connecticut, 06520, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Able to participate in an eye-tracking experiment
  • Able to participate in an EEG experiment

Exclusion criteria

  • Sensory or physical impairment that would preclude completion of protocol
  • Participants taking prescription medications that may affect cognitive processes
  • Participants reporting significant head trauma or history of seizures

Treatment and study plan

Game

Behavioral

Primary outcomes

  1. EEG brain response to targets

    Time frame: Measures will be recorded for the duration of their visit, an expected average of 3 hours.

Secondary outcomes

  1. Visual attention to targets as measured by eye-tracking

    Time frame: Measures will be recorded for the duration of their visit, an expected average of 3 hours.

  2. Social Responsiveness Scale, Second Edition

    Time frame: Measures will be collected during visit, an expected average of 3 hours.

  3. Autism Diagnostic Observation Schedule

    Time frame: Measures will be collected during visit, an expected average of 3 hours.

  4. Differential Abilities Scale

    Time frame: Measures will be collected during visit, an expected average of 3 hours.

  5. Vineland Adaptive Behavior Scales, Second Edition

    Time frame: Measures will be collected during visit, an expected average of 3 hours.

  6. Social Anxiety Scale for Children, Revised

    Time frame: Measures will be collected during visit, an expected average of 3 hours.

Sponsors and collaborators

Lead sponsor

Yale University

Other

Registry information

Important dates

Study start
2014
Primary completion
2026
Study completion
2026
First posted
Apr 21, 2014
Registry last updated
May 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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