Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole

The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation.

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Key information

Conditions

Hyperemia Cardiovascular Diseases Hypoxia Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Respiratory Vascular Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Radboud university Nijmegen Medical Centre

Nijmegen, Gelderland, 6533 ZA, Netherlands

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy volunteers between 18 and 50 years

Exclusion criteria

none specified

Treatment and study plan

dipyridamole

Drug

Caffeine

Drug

Primary outcomes

forearm blood flow

Sponsors and collaborators

Lead sponsor

Radboud University Medical Center

Other

Registry information

Official study title

Enhancement of Postocclusive Reactive Hyperaemia

Important dates

Study start: 2005
Study completion: 2006
First posted: Dec 22, 2005
Registry last updated: Mar 28, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed