faculty of medicine-Cairo university
Cairo, Egypt
NCT Number: NCT07564063
This prospective randomized controlled clinical trial aims to evaluate the effectiveness of Enhanced Recovery After Surgery (ERAS) protocols in patients undergoing elective hysterectomy. ERAS is an evidence-based perioperative approach designed to reduce surgical stress, accelerate recovery, and improve clinical outcomes. Participants will be randomized to receive either ERAS-based care or conventional perioperative management. The study will assess whether ERAS implementation reduces hospital stay and improves postoperative recovery without increasing complications.
Trial opening soon.
Get Notified18 year–70 year
Female
Interventional
Not applicable
Cairo, Egypt
Enhanced Recovery After Surgery (ERAS) protocols are structured, multidisciplinary perioperative care pathways developed to optimize surgical outcomes by minimizing physiological stress and promoting early recovery. These protocols include preoperative counseling, shortened fasting with carbohydrate loading, opioid-sparing anesthesia, early feeding, and early mobilization.
Hysterectomy remains one of the most common gynecological procedures worldwide and is often associated with prolonged hospital stay and postoperative morbidity, particularly in resource-limited settings. While international evidence supports the benefits of ERAS in improving outcomes such as reduced length of hospital stay, improved pain control, and decreased complications, there is a need for locally generated data to validate its effectiveness in Egyptian tertiary healthcare settings.
This study will be conducted at Kasr Al-Ainy Hospital, Cairo University, and will include women undergoing elective hysterectomy for benign or early-stage malignant gynecological conditions. Participants will be randomly assigned to either the ERAS group or the conventional care group. Outcomes will be assessed during hospitalization and up to 30 days postoperatively.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
IV dextrose infusion (5%) 500 ml once ,2-3 hours before anesthesia
Reduced fasting Early oral feeding Early mobilization
Time frame: From day of surgery up to 7 postoperative days
Time from completion of surgery to hospital discharge readiness, measured in days.
Time frame: At 12 and 24 hours postoperatively
Postoperative pain intensity measured using the Visual Analog Scale (VAS), a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain).
Time frame: Up to 5 postoperative days
the interval (in hours) from completion of surgery to the first documented passage of stool."
Contact information is provided by the study sponsor or research team.
Ehab H Sorour, MD
CONTACT
Mohamed E El Mahy, MD
CONTACT
Cairo University
Other
Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols in Hysterectomy Patients. A Prospective,Randomized Controlled Clinical Trial.
Acronym: ERAS
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07602231
Ambulatory Surgery, Anterior Cruciate Ligament Injuries
View Trial DetailsNCT07482345
Enhanced Recovery After Surgery (ERAS) Protocol, Pediatric Surgery
Bursa, Turkey (Türkiye)
View Trial DetailsNCT05576766
Enhanced Recovery After Surgery (ERAS) Protocol, Genital Diseases
Beijing, Beijing Municipality, China
View Trial DetailsNCT07396077
Enhanced Recovery After Surgery (ERAS) Protocol, Frail Elderly
Beijing, Beijing Municipality, China
View Trial Details