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NCT Number: NCT06530433

Enhanced Community First Responder System Evaluation in Singapore

The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR). Despite many lay responders performing CPR, survival rates with good neurological outcomes have not significantly improved, prompting research into the quality of CPR as a critical factor. The study by Gallagher EJ et al. showed a significant survival improvement with high-quality CPR.

To address this, the Unit of Pre-hospital and Emergency Research (UPEC) trained thousands of community first responders (CFRs) in simplified CPR techniques using hands-only and DA-CPR methods. A significant innovation is the CPRcard®, developed by Laerdal in Norway, which offers real-time feedback on the quality of chest compressions. However, only 36% of CFRs using the CPRcard® achieved the desired compression standards, indicating room for improvement.

The study proposes enhancing CFR support with information communication technology (ICT), enabling two-way audio and one-way video communication between CFRs and dispatchers. This aims to reduce stress among responders, increase their willingness to engage with OHCA alerts, and improve CPR quality.

The clinical trial in Singapore will compare the current system against the enhanced CFR support system (eCSS), focusing on the real-time relay of CPR performance data, communication ease, and implementation factors. The high-quality CFR and OHCA registries in Singapore provide a robust setting for this research, aiming to enhance CPR delivery and improve OHCA outcomes through technology and real-time support.

Recruiting

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years old and above
  • SCDF registered CFRs
  • Trial dispatchers with an active account of myResponder® app on their mobile phones

Exclusion criteria

  • The CFRs who are pregnant
  • Experiencing any serious physical Conditions
  • Mental Health Conditions

Treatment and study plan

CPRCard + TCPR Link App and Web

Device

Application that allows responder to perform CPR with two-way audio communication and one-way video streaming to SCDF Dispatcher

CPRCard Only

Device

Control arm with standard care of procedure that Bystander using CPRCard only

Primary outcomes

  1. Good Chest Compression Depth (4-6cm)

    Time frame: Throughout chest compression before handing over to EMS (up to 24 hours)

    OHCA events achieving great proportions of adequate compressions (achieving depth within the target range of 4-6 cm)

Secondary outcomes

  1. Survivor discharging rate

    Time frame: Throughout Hospital Admission (up to 1 year)

    Return of spontaneous circulation (ROSC) at scene or at emergency department; survival to discharge; neurologically intact survival

Study contacts

Contact information is provided by the study sponsor or research team.

Alexander A White, MSc

CONTACT

[email protected]

+65 90674081

Fahad J Siddiqui, MSc

CONTACT

[email protected]

+6566017951

Sponsors and collaborators

Lead sponsor

Singapore General Hospital

Other

Collaborators

  • Duke-NUS Graduate Medical School

Registry information

Official study title

Evaluation of an Enhanced Community First Responder Support System to Improve Bystander Cardiopulmonary Resuscitation Quality for Patients Experiencing Out-of-hospital Cardiac Arrest

Acronym: TCPR-Link

Important dates

Study start
2024
Primary completion
2027
Study completion
2028
First posted
Jul 31, 2024
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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