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Completed

NCT Number: NCT04279964

Engaging Practices and Communities in the Development of Interventions to Promote HPV Vaccine Uptake

The overarching goal of this project is to implement Boot Camp Translation (BCT) methodology to translate the guidelines and evidence for human papillomavirus (HPV) vaccine into a practice and provider level intervention designed to improve its acceptability and uptake.

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Key information

Conditions

Age range

9 year–26 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Colorado Hospital

Aurora, Colorado, 80045, United States

About this study

As a community engagement approach, Boot Camp Translation (BCT), is a 6-9-month iterative process that brings together multiple stakeholders, including patients, parents, and community members, to translate evidence-based guidelines and recommendations into locally relevant and meaningful messages, materials, and programs.

Aim 1: Implement BCT in three geographically distinct Colorado communities to translate the current evidence for HPV vaccination into locally relevant interventions designed to increase vaccine uptake.

Aim 2: Evaluate the impact of the BCT- designed intervention on practice-level HPV vaccination initiation rates.

The long-term goal is to develop a replicable approach and low-cost method of increasing HPV vaccine uptake that is easily adaptable to different settings and sociodemographic contexts.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All child patients who have received health supervision at participating practices during the 12 month prior to intervention and the 12 month following intervention implementation, who are ages 9-26 years, and whose parents have not requested removal from the Colorado Immunization Information System (CIIS) will be eligible for the assessment of practice immunization rates in the pre and post periods.

Exclusion criteria

  • No subjects will be excluded because of gender, ethnicity, or insurance status.
  • Any child whose parents have requested removal from the immunization registry; any child with hypersensitivity to any component of one of the recommended vaccines; any child who has moved to a primary care provider other than one at the study clinics.

Treatment and study plan

Boot Camp Translation

Behavioral

Practices in the intervention arm will participate in the Boot Camp Translation process, where BCT Community Advisory group members will come together to develop and implement practice relevant materials to promote adolescent vaccination.

Control

Other

No intervention. Practices will continue to behave as usual.

Primary outcomes

  1. Initiation of HPV vaccination series, 9-17

    Time frame: Up to 12 months

    Percent of 9-17 year olds who have received >=1 dose of the HPV vaccine by September 29, 2021

Secondary outcomes

  1. Differences in initiation rates between intervention vs. control, 9-10

    Time frame: 12 months

    Comparison of boys vs. girls who have received >1=dose of HPV vaccine by September 29, 2021

  2. Differences in initiation rates between intervention vs. control, 11-12

    Time frame: 12 months

    Comparison of boys vs. girls who have received >1=dose of HPV vaccine by September 29, 2021

  3. Differences in initiation rates between intervention vs. control, 13-17

    Time frame: 12 months

    Comparison of boys vs. girls who have received >1=dose of HPV vaccine by September 29, 2021

  4. Differences in initiation rates between intervention vs. control, 18-26

    Time frame: 12 months

    Percent of 18-26 year olds who have received >=1 dose of the HPV vaccine by September 29, 2021

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Collaborators

  • National Cancer Institute (NCI)
  • National Institutes of Health (NIH)

Registry information

Important dates

Study start
2020
Primary completion
2024
Study completion
2024
First posted
Feb 21, 2020
Registry last updated
Apr 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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