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Enrolling by Invitation

NCT Number: NCT07399912

Engaging Home-monitored Assessment to Navigate Clinical Decision-making

This study is testing a new app called ENHANCe, which is designed to help family doctors manage patients with high blood pressure using readings taken at home.

Enrolling by Invitation

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

SingHealth Polyclinics

Singapore, 150167

About this study

The researchers want to find out if the app is easy to use in everyday clinic settings, whether doctors find it helpful and are willing to use it, and if it helps improve care. The study will involve 16 doctors and 100 patients with high blood pressure, split into two groups at two clinics. One group will use the ENHANCe app, which can read blood pressure data from different sources-including handwritten notes-and give doctors advice based on that information. The other group will receive regular care without the app. Over six months, researchers will collect feedback from doctors through surveys and group discussions at the end of the study. They'll also track how many people complete the study, how long clinic visits take, whether doctors follow the app's advice, and how well patients' blood pressure is controlled. The goal is to see if the app can help doctors make faster, better decisions and improve health outcomes for people managing their blood pressure at home.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

For primary care physicians:

  • PCPs aged 21 years and above.
  • Involved in the clinical management of patients with hypertension in the past six months.

For patients:

  • Patients aged 21 years and above
  • Documentation of hypertension diagnosis in EMR
  • Owns an HBP monitoring device

Exclusion criteria

for patients:

  • Documentation of dementia diagnosis in EMR
  • Audio or visual impairments
  • Hypertensive urgency or emergency

Treatment and study plan

ENHANCe app

Device

ENHANCe app is a prototype; it is a smartphone based clinical decision support (CDS) tool to manage patients with hypertension using their home blood pressure. The app will scan patients' home BP records from paper or mobile phone, and provide a recommendation to the doctor on how to manage their blood pressure. The patient will not need to use the device during the study period. However, the recommendation from the ENHANCe app will be available to the doctor to manage your blood pressure during the study period if the patient is in the intervention group.

Teaching and training

Other

All patients will have access to online educational resources throughout the study. After recruitment, they will receive a nurse-led education on HBP monitoring. The research team will train all primary care physicians (PCPs) on managing patients with hypertension using HBP records.

Usual Care

Other

Physicians manage patients using HBP records at their discretion

Primary outcomes

  1. Response rate of participants

    Time frame: 6 months

    Participants agreeable to participate in the study

  2. Agreement with the CDSS recommendation among PCPs

    Time frame: 6 months

    Proportion of PCPs who agree with the CDSS recommendation in the two groups

  3. Withdrawal rate

    Time frame: 6 months

    Proportion of participants who withdrew

  4. Study completion rate

    Time frame: 6 months

    Proportion of participants who completed the intervention

  5. Adverse event rates

    Time frame: 6 months

    Proportion of adverse events reported in the two groups

  6. Consult duration

    Time frame: 6 months

    Consult time in the groups

  7. Ease of home blood pressure record assessment among PCPS

    Time frame: 6 months

    Ease of home blood pressure record assessment among PCPS in the two arms

Secondary outcomes

  1. Proportion of CDSS recommendation followed by the PCPS

    Time frame: 6 months

    Proportion of ENHANCe recommendations followed by the PCPs among the two groups

  2. Blood pressure control status

    Time frame: 6 months

    Blood pressure control status among patients in the two groups

Sponsors and collaborators

Lead sponsor

SingHealth Polyclinics

Other

Collaborators

  • Nanyang Polytechnic

Registry information

Official study title

Engaging Home-monitored Assessment to Navigate Clinical Decision-making -The ENHANCe Study

Acronym: ENHANCe

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 10, 2026
Registry last updated
Feb 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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