University of Florida
Gainesville, Florida, 32611, United States
NCT Number: NCT03324256
The purpose of this study will be to examine the acute effect of commercially available energy products on endothelial function, arterial stiffness and thrombosis in healthy young males.
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Notify Me18 year–30 year
Male
Interventional
Not applicable
Gainesville, Florida, 32611, United States
The use of energy products has significantly increased in the last few years and is especially high among young men. The present study will compare the acute effect of a commercially available energy drink, energy gum, coffee and control beverage on endothelial function, arterial stiffness and circulating markers of thrombosis, inflammation and oxidative stress.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
16 oz cold commercially-available energy drink
16oz cold commercially-available caffeinated drink
2 pieces of commercially-available energy gum
2 pieces of commercially-available placebo gum
16oz cold control drink
24-hour total sleep deprivation prior to consumption of energy drink and placebo gum
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Brachial artery flow-mediated dilation
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Carotid to femoral pulse wave velocity
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Augmentation index
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Brachial and aortic blood pressures
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Thromboelastograph and platelet aggregation tests
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Circulating levels of Trimethylamine N-oxide (TMAO) and markers of oxidative stress and inflammation
Time frame: Before and 1 and 2 hrs following consumption of drink and gum
Electrocardiogram
University of Florida
Other
Acute Effect of Energy Drinks on Vascular Function
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