Endovascular Treatment for Chronic Cerebrospinal Venous Insufficiency (CCSVI)

The aim of this study is to assess the efficacy of endovascular treatment (balloon angioplasty and/or stenting) for the improvement of clinical symptoms in multiple sclerosis patients.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Cardiovascular Diseases Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases Vascular Diseases Venous Insufficiency

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Euromedic Specialist Clinics

Katowice, Poland

About this study

The aim of this study is to assess the efficacy of endovascular treatment (balloon angioplasty and/or stenting) for the improvement of clinical symptoms in multiple sclerosis patients measured by Extended Disability Severity Score (EDSS), Multiple Sclerosis Impact Scale-29 (MSIS-29), Fatigue Severity Scale (FSS) and heat intolerance

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with clinically defined multiple sclerosis

Exclusion criteria

contraindication for endovascular procedure performed in local anesthesia

Treatment and study plan

balloon angioplasty and/or stenting

Procedure

balloon angioplasty and/or stenting of internal jugular veins and/or azygous vein and/or brachiocephalic veins

Primary outcomes

Change in clinical symptoms of multiple sclerosis measured by Extended Disability Severity Score (EDSS), Multiple Sclerosis Impact Scale-29 (MSIS-29), Fatigue Severity Scale (FSS) and heat intolerance

Time frame: 6 months after the procedure

Sponsors and collaborators

Lead sponsor

Euromedic Specialist Clinics, Poland

Other

Registry information

Official study title

Endovascular Correction of Chronic Cerebrospinal Venous Insufficiency (CCSVI) and Evaluation of Influence of These Treatments on the Symptoms of Multiple Sclerosis

Important dates

Study start: 2010
Primary completion: 2010
Study completion: 2012
First posted: Dec 22, 2010
Registry last updated: Feb 10, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed