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OpenTrials
Completed

NCT Number: NCT00660491

Endothelial Dysfunction Induced by Postprandial Lipemia

Postprandial lipemia and exercise oppose each other in terms of cardiovascular risk, however the mechanism of their interaction is not well understood.

Therefore we want to study vascular function, as assessed by brachial artery (BA) flow mediated dilation (FMD), in healthy men before and after a high fat meal (HFM) preceded (16-18 hrs) by rest, a single bout of continuous moderate intensity exercise (CME), and high intensity interval exercise (HIIE).

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Key information

Conditions

Age range

20 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 2

Primary location

NTNU

Trondheim, 7489, Norway

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male, 20-40years, BMI between 25 and 30, resident in Trondheim.

Exclusion criteria

  • unstable angina, CHD, heart failure,

Treatment and study plan

Exercise training

Other

moderate intensity exercise group, and high intensity exercise group

Primary outcomes

  1. Flow mediated dilatation

    Time frame: baseline, post exercise, 30min, 2hour, 4hour post exercise

Secondary outcomes

  1. blood lipid profile

    Time frame: same as flow mediated dilatation

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Registry information

Official study title

Endothelial Dysfunction Induced by Postprandial Lipemia: Complete Protection Afforded by High Intensity Aerobic Interval Exercise

Important dates

Study start
2008
Primary completion
2008
Study completion
2008
First posted
Apr 17, 2008
Registry last updated
Jan 6, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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