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OpenTrials
Completed

NCT Number: NCT06553326

EndoStyle: Artificial Intelligence Image Transformation Tool for Colonoscopy

The study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images. The investigators aim to develop and validate EndoStyle, an AI system that can generate images in the style of various processors from a single reference image. EndoStyle will be tested by showing endoscopists colonoscopy sequences with different image types to determine if they can distinguish AI-transformed images. Success would enhance AI training for diverse clinical setups.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Clinic of Würzburg

Würzburg, Bavaria, 97080, Germany

About this study

The use of artificial intelligence (AI) in gastrointestinal endoscopy has become widespread. However, these systems are often only trained with data from a single type of endoscopy processor, which limits their applicability. In addition, the availability of images annotated by experts is limited, which affects data variability and thus the performance of AI systems.

The aim of this study is to develop a new artificial intelligence (AI) based system (EndoStyle) and validate its authenticity by means of a survey among physicians, which is able to generate multiple images in the style of different processor types (including Olympus, Pentax and Storz) from a single endoscopy reference image.

The investigators hypothesis is that the AI system is able to successfully change the image style of video processors, with the differences being imperceptible to the endoscopist's eye.

The methodology consists of showing to multiple endoscopists 28 colonoscopy sequences of 10 seconds duration each. In each one of them 3 images will be shown that can be all the possible combinations of images belonging to positive control, negative control, and Endostyle (intervention group). By performing a statistical comparison of the percentages of selected images for each group the investigators will be able to establish whether the participants are able to distinguish the images transformed by the AI.

If the results corroborate our hypothesis, our system could generate images that would allow a more customized training of AI systems for each clinical setup.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Physicians with experience in colonoscopy.

Treatment and study plan

EndoStyle

Device

The EndoStyle system is able to transform the style of the different video-processor images.

Primary outcomes

  1. Perceptual Indistinguishability of AI-Transformed Endoscopic Images

    Time frame: 5 months

    Comparison of the accuracy for each study group.

Secondary outcomes

  1. Time Taken for Image Identification

    Time frame: 5 months

    Time taken to assess the different tasks according to each study group.

  2. Influence of regularly used processor

    Time frame: 5 months

    Influence of regularly used endscopy processor during clinical work for the perceptual indistinguishability of AI-transformed endoscopic images with defined processor classes

  3. Influence of endoscopy experience

    Time frame: 5 months

    Influence of experience in endoscopy measured in lifetime performed colonscopies on perceptual indistinguishability of AI-transformed endoscopic images

Sponsors and collaborators

Lead sponsor

Wuerzburg University Hospital

Other

Registry information

Official study title

EndoStyle: Survey of Physicians on Endoscopic Image Style Transfer.

Acronym: EndoStyle

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 14, 2024
Registry last updated
Sep 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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