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Completed

NCT Number: NCT05155475

Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies (ECCO Trial)

To assess the size of the common bile duct in a large cohort of patients with jaundice following a malignant tumor of the head of the pancreas or the distal bile duct receiving a diagnostic EA for biopsy and / or for evaluation of tissue resectability.

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Key information

Conditions

Obstructive Jaundice Bilio-pancreatic Tumor Hyperbilirubinemia Jaundice Jaundice, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Signs and Symptoms Skin Manifestations

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hôpital Jean Mermoz

Lyon, 69008 Lyon, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with jaundice and an injury to the head of the pancreas recommended for EUS-guided tissue acquisition or staging
  • Patients with jaundice and distal CBD lesion suggestive of cholangiocarcinoma or Vater's ampulla carcinoma recommended for EUS-guided tissue acquisition or staging
  • Serum bilirubin level ≥ 3 mg / dl
  • Age ≥ 18 years old
  • Subject affiliated or beneficiary of a social security scheme.
  • Subject having been informed of this study and having given his no objection

Exclusion criteria

  • Presence of altered anatomy due to previous gastric surgery (Billroth II or Roux-en-Y anastomosis)
  • Sphincterotomy performed previously, plastic biliary stent or metal stent placement
  • Percutaneous drainage of the bile ducts performed previously
  • Pregnant, breastfeeding or parturient woman
  • Protected patients: Adults under guardianship, curatorship or other legal protection, deprived of their liberty by judicial or administrative decision; hospitalized without consent.

Treatment and study plan

Ultrasound endoscopy

Procedure

After identification of the lesion, the common bile duct will be identified and followed by the point of dilation due to the compression of the known lesion up to the hilum of the liver

Primary outcomes

  1. Evaluation of the common bile duct size

    Time frame: 1 day

Sponsors and collaborators

Lead sponsor

GCS Ramsay Santé pour l'Enseignement et la Recherche

Other

Collaborators

  • European Clinical Trial Experts Network

Registry information

Official study title

Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies: a Multicenter Prospective Study (ECCO Trial)

Acronym: ECCO

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Dec 13, 2021
Registry last updated
Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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