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NCT Number: NCT06886880

Endoscopic Findings in Patients With Upper GIT Bleeding

This study aims to identify the causes of upper gastrointestinal bleeding through comprehensive evaluation via upper endoscopy in Assiut University Hospital and contribute valuable insights into effective management strategies.

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Key information

About this study

Upper gastrointestinal bleeding (UGIB) is a critical medical situation that arises when there is bleeding proximal to the ligament of Treitz [1]. This condition is a leading cause of morbidity and mortality, with death rates ranging from 5-14% and increasing to over 40% in patients with liver disease[2] Symptoms of UGIB may include anemia, hematemesis, melena, or hematochezia [3].

Neoplasms, arteriovenous malformations, esophageal varices, gastric ulcers, gastric erosions, duodenal ulcers, reflux esophagitis, Mallory-Weiss tears, and fundal varices are causes of UGIB [4].

Current strategies for managing UGIB emphasize early recognition and intervention. Endoscopy is the primary diagnostic and therapeutic modality, allowing for direct visualization of the gastrointestinal tract and enabling interventions such as cauterization, clipping, or band ligation to control bleeding [5]. Recent advancements in endoscopic techniques have improved outcomes by facilitating earlier detection and treatment of UGIB episodes. For instance, the use of hemostatic powders and over-the-scope clips has shown promise in managing refractory cases[6,7].

Endoscopic therapies may have resulted in earlier detection and treatment of UGIB, which could have led to a reduction in the incidence and severity of the condition. Upper GI endoscopy is considered the primary modality for identifying the underlying etiology and administering appropriate therapeutic measures to the patient present with upper GIT bleeding by ligation ,clips, electrocoagulation or by taking biopsies that help in diagnosis. The rationale for this research stems from the need to enhance understanding of UGIB's underlying causes and improve patient outcomes through timely endoscopic intervention. By identifying specific etiologies through upper endoscopy[8,9].

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients present with upper GIT bleeding of both gender older than 18 years old

Exclusion criteria

  • 1- Patients younger than 18 2- Pregnant women 3- patients with end stage disease that not fit for endoscopic intervention

Treatment and study plan

endoscope

Device

findings in upper GIT Endoscopy

Primary outcomes

  1. Endoscopic Findings in patients with upper GIT Bleeding

    Time frame: one year

    identify the causes of upper gastrointestinal bleeding through comprehensive evaluation via upper endoscopy in Assuit University Hospital and contribute valuable insights into effective management strategies.

Study contacts

Contact information is provided by the study sponsor or research team.

Abd alhamed mhamed

CONTACT

[email protected]

01012125291

Ebram Sala,ma

CONTACT

[email protected]

01280541696

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Endoscopic Findings in Patients With Upper GIT Bleeding in Assiut University Hospital

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Mar 20, 2025
Registry last updated
Mar 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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