The Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, 510655, China
NCT Number: NCT06165289
The aim was to investigate whether endoscopic balloon dilatation combined with PRP injection can help prevent or prolong restenosis in patients with Crohn's disease with colonic stenosis, and to explore the concentration of PRP. The study was a single-center, randomized, non-controlled study. Experimental group of patients underwent endoscopic balloon dilation and submucosal injection of PRP at the wound edge, historical control was used, and the patients included in the study were randomly divided into high concentration group and low concentration group.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Guangzhou, Guangdong, 510655, China
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Endoscopic balloon dilatation combined with autologous platelet-rich plasma (PRP) injection with different concerntrations
Time frame: 3 months after endotherapy
restenosis means the endoscopy with size of 10.5mm can not pass the stricture afer endotherapy
Time frame: 3 months after endotherapy
the thickness of the stricture intestinal wall, and the width of the proximal intestinal cavity
Time frame: 1 year after endotherapy
The proportion of surgery due to stenosis or perforation
Sixth Affiliated Hospital, Sun Yat-sen University
Other
Efficacy and Safety of Endoscopic Balloon Dilatation Combined With Autologous Platelet-rich Plasma (PRP) Injection in Colonic Stenosis in Crohn's Disease
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