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Completed

NCT Number: NCT01778452

Endometrial Genomic Profile in Endometrial Priming

The aim of this study is to analyse genomics profile expression in endometrium under different endometrial priming for recipients.

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Key information

Conditions

Genomic Human Endometrial Expression Profile

Age range

18 year–35 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Ivi Valencia

Valencia, 46015, Spain

About this study

We analyze the genomic profile of egg donors in different endometrial priming protocols, compared with natural cycle, including the conventional single long acting GnRH agonist injection in the mid luteal phase of the previous cycle of the endometrial priming and the single daily antagonist injection (Cetrorelix 0.25 mg) administered in the early follicular phase followed by endometrial priming. Endometrial biopsy will be taken in luteinizing hormone

  • 7 or with P4 +5 in cases with endometrial priming with oestrogens therapy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 6 egg healthy volunteer egg donors.
  • Volunteers.
  • 18-35 years old
  • Healthy.
  • BMI <28.

Exclusion criteria

  • - BMI > 28
  • Smokers-

Treatment and study plan

endometrial biopsy

Procedure

endometrial biopsy

Primary outcomes

  1. genetic endometrial human profile expression

    Time frame: Oocyte donors will be followed up for four to six months

    implantation related genes profile expression

Sponsors and collaborators

Lead sponsor

Instituto Valenciano de Infertilidad, IVI VALENCIA

Other

Collaborators

  • Igenomix

Registry information

Official study title

Profile Study of Genomics Endometrial Expression After Gonadotropin-releasing Hormone Agonist Administration and GnRH in Endometrial Priming.

Important dates

Study start
2009
Primary completion
2012
Study completion
2013
First posted
Jan 29, 2013
Registry last updated
Feb 15, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.