Skip to main content
OpenTrials
Completed

NCT Number: NCT07662187

Endometrial Cavity After Conservative Management of PAS Patients by Hysteroscopy

This study aimed to evaluate the endometrial cavity by hysteroscopy after different conservative management of placenta accrete spectrum (PAS), that has impact on the future fertility outcome and menstrual pattern of patients.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Uterine Cavity Conservative Management Female Urogenital Diseases and Pregnancy Complications Obstetric Labor Complications Placenta Accreta Placenta Diseases Pregnancy Complications Urogenital Diseases

Age range

20 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Sohag University

Sohag, 82511, Egypt

About this study

Placenta Accreta Spectrum is usually associated with maternal morbidity and mortality. The morbidly adherent placenta spectrum includes, placenta accreta when the placenta invades the endometrium beyond Nitabuch's layer of decidua basalis, placenta increta when the placenta invades the myometrium, and placenta percreta when the placenta invades the uterine serosa.

The risk factors of PAS include previous caesarean section (CS), previous myomectomy, placenta previa, and damage of Nitabuch's layer following intrauterine infection and/or endometrial curettage.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age from 20 to 40 years.
  • Pregnant women more than 28 weeks have a desire to preserve future fertility.
  • Diagnosis of Placenta accreta spectrum (PAS) was evaluated by 2 D grey scale ultrasound and Doppler study of invasion of the placenta.
  • History of at least previous caesarean section (CS) or any intrauterine operation like myomectomy.
  • Females with history of different conservatives management methods of PAS in last three months.

Exclusion criteria

  • Non placenta accreta spectrum and primigravida.
  • Those who have congenital anomalies in the uterus.
  • Those with bleeding tendency.
  • Those women that had hysterectomy as a radical surgery.

Treatment and study plan

Resection and reconstruction

Procedure

Patients underwent resection and reconstruction.

Cervical eversion and pouch closure

Procedure

Patients underwent cervical eversion and pouch closure.

Anterior and posterior sutures

Procedure

Patients underwent anterior and posterior sutures.

Primary outcomes

  1. Number of participants with restoration of the endometrial cavity assessed by office hysteroscopy

    Time frame: 3 months after cesarean section

    Assessment of endometrial cavity restoration by office hysteroscopy 3 months after conservative management of placenta accreta spectrum.

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Evaluation of Endometrial Cavity After Conservative Management of PAS Patients by Hysteroscopy

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jun 23, 2026
Registry last updated
Jun 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.