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Completed

NCT Number: NCT00953628

Endometrial Advancement After Rec or u-HCG Triggering

The purpose of this study is to investigate any potential advantages of replacing human chorionic gonadotropin (uhCG) with recombinant human chorionic gonadotropin (recHCG) for final oocyte maturation with regard to Ovarian hyperstimulation syndrome (OHSS)pathophysiology, endometrium receptivity and embryo quality and clinical pregnancy.

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

20 year–36 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Centre for Reproductive Medicine, UZ Brussel

Brussels, Jette, 1090, Belgium

About this study

Biopsies of endometrium were taken in different groups Pregnancy rates were compared among defferent groups

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Less than 36 years old
  • Male or tubal infertility
  • FSH<12 on day 3

Exclusion criteria

  • Endometriosis stage 3 & 4

Treatment and study plan

10000 IU urinary HCG

Drug

bolus 10000 units for ovulation triggering

Other names: Pregnyl

250 mcg recombinant HCG

Drug

bolus 250 mcg for ovulation triggering in IVF patients

Other names: Ovitrelle

Primary outcomes

  1. endometrium histology on the day of OPU

    Time frame: day of oocytre pick up

Secondary outcomes

  1. pregnancy rate

    Time frame: 14 days after oocyte pick up

Sponsors and collaborators

Lead sponsor

Universitair Ziekenhuis Brussel

Other

Collaborators

  • Merck Serono International SA

Registry information

Important dates

Study start
2005
Primary completion
2006
Study completion
2008
First posted
Aug 6, 2009
Registry last updated
Dec 3, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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