Endodontic Medications for Irreversible Pulpitis: Articaine or Eugenol?

The objective of the study is to determine which of the two commonly used endodontic medications (Eugenol VS Articaine) is most effective in controlling postoperative pain in irreversible pulpitis of the mature permanent tooth in adults. To do so, an assessment of the pain felt by patients will be carried out a few days apart. The supposed results are that the medications are equivalent in terms of effectiveness on the pain, but could then present different economic arguments

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Key information

Conditions

Pulpitides Dental Pulp Diseases Endodontic Inflammation Facial Pain Neurologic Manifestations Operative Dentistry Pain Pathological Conditions, Signs and Symptoms Pulpitis Signs and Symptoms Stomatognathic Diseases Tooth Diseases Toothache Toothaches

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Les Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

About this study

In irreversible pulpitis of the mature permanent tooth, the enrolled patients receive endodontic medications (Eugenol or Articaine) in order to determine which one is the more efficient to control the pain.

These patients would have received the same medication without this study. That's why this is an obsevationnal study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patient, major, affiliated to a social health insurance scheme
Patient having agreed to participate in the study
Urgent consultant patient for irreversible pulpitis
Patient understanding French

Exclusion criteria

Refusal of the patient to participate in the study
Impossibility of performing the surgical procedure
Impossibility to give the subject information enlightened (difficulty of understanding ...)
Subject under the protection of justice, or under guardianship
General contraindication to endodontic treatment in 2 sessions (high risk of infectious endocarditis, for example)
Chronic intake of analgesic drugs

Treatment and study plan

Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne

Drug

Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne

Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol

Drug

Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol

Primary outcomes

Pain evolution (decrease or increase the intensity of the pain)

Time frame: 7 days

Evolution of pain (using a score of 0 to 10)

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Official study title

Articaine or Eugenol: a Study on the Choice of Endodontic Medication in the Emergency Management of Irreversible Pulpitis of a Mature Permanent Tooth

Important dates

Study start: 2018
Primary completion: 2018
Study completion: 2019
First posted: Mar 21, 2018
Registry last updated: Sep 17, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed