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NCT Number: NCT07045025

Endodontic Errors Detected by CBCT in Egypt

This observational cross-sectional study aims to evaluate the prevalence of endodontic procedural errors in root canal-treated teeth among an Egyptian subpopulation using cone-beam computed tomography (CBCT). The study will analyze CBCT scans obtained from radiology centers in Cairo to detect errors such as missed canals, short fillings, perforations, fractured instruments, and other complications. Understanding the frequency and distribution of these errors between the maxillary and mandibular arches may help improve endodontic treatment outcomes and raise awareness of common procedural challenges. The study does not involve any new treatment or drug but will rely on previously taken CBCT images.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The biological and therapeutic goals of Endodontic treatment are to prevent apical lesions or to establish ideal healing conditions by removing bacteria and infection from the root canal system and preventing reinfection. However, endodontic mishaps such as incorrect diagnosis, missed canals, perforations, instrument separation, over- or under-obturation, and vertical root fractures compromise the success of root canal therapy.

The reported success rate of endodontic treatments by general dentists ranges from 60% to 75%. Procedural errors are a significant factor contributing to the suboptimal success rate of endodontic treatments performed by general dentists. Moreover, the global prevalence of periapical lesion is approximately 52% in individuals and 5% in teeth, with higher frequency in teeth with root-filled teeth compered to non-treated teeth.

Procedural errors may be difficult to correct. Certain procedural errors could need endodontic retreatment, apicoectomy, or even tooth extraction. Root canal transportation, apical perforation, strip perforation, access cavity perforation, and instrument fracture are among the commonly occurring procedural errors. The working length of the root canal filling is a critical factor, with fillings short of the apex by 2 mm reducing success rates to 68-77% and overfills beyond the apex yielding around 75% success rates.

Endodontic treatment for molar teeth is more challenging and requires more caution than anterior and premolar teeth, and is associated with a higher rate of procedural errors. The reason for this is their difficulty in accessibility and anatomical complexity. This is reflected in the distribution of errors, were Procedural errors were more frequently observed in mandibular teeth (53.1%) than maxillary teeth (46.9%), with the highest error rate found in the right and left permanent mandibular first molars (20.2% and 14.3%, respectively).

Cone-beam computed tomography (CBCT) it delivers high-quality images and images providing three-dimensional imaging, allowing detailed views of individual teeth from any angle. This makes it an effective tool for diagnosing, planning, and monitoring endodontic treatment. CBCT can detect periapical radiolucency before they would be apparent on conventional radiographs. While traditional radiographs are less expensive and expose patients to lower radiation doses, research has demonstrated that CBCT images are better for diagnosing periapical lesions.

Rationale for conducting the research:

In Egypt, there is a lack of comprehensive data regarding the prevalence and distribution of procedural errors in endodontically treated teeth. This knowledge gap limits our understanding of how these errors differ between the maxilla and mandible and restricts the development of targeted strategies to enhance treatment quality and reduce failure rates.

Despite significant advancements in endodontic techniques and imaging modalities, procedural errors remain a critical challenge in achieving optimal treatment outcomes. These errors are particularly problematic in molar teeth due to their anatomical complexity and reduced accessibility. Although several international studies have evaluated the prevalence of endodontic procedural errors, there is limited research focusing specifically on the Egyptian subpopulation.

Understanding the patterns and frequencies of procedural errors in maxillary and mandibular teeth among Egyptians can aid clinicians in anticipating challenges, refining treatment strategies, and minimizing procedural failures. Moreover, differences in error distribution between the two jaws reported in other populations highlight the need for local investigation.

CBCT technology provides a detailed three-dimensional assessment of dental anatomy and procedural errors, offering superior diagnostic capabilities compared to two-dimensional radiography. This makes it an ideal tool for evaluating the prevalence and distribution of endodontic procedural errors.

Therefore, the aim of this study is to determine the prevalence and distribution of endodontic procedural errors in the maxilla and mandible using CBCT imaging in a selected Egyptian subpopulation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • CBCT scans showing at least one permanent tooth that has undergone complete root canal treatment.
  • Scans showing both jaw (maxilla and mandible) .
  • Scans with good image quality and a voxel size of 0.2 mm or 0.3 mm.
  • Egyptian nationals of either gender.
  • Age over 18 years.

Exclusion criteria

  • CBCT scans that do not show any teeth with complete root canal treatment.
  • Completely edentulous patient.
  • Low-quality images or scans with artefacts.
  • Scans with voxel size larger than 0.3 mm.
  • Non- Egyptian patients.
  • Surgically treated endodontic cases (e.g., apicoectomy).

Treatment and study plan

No Clinical Intervention - Analysis of Previously Acquired CBCT Scans

Other

This study does not involve any clinical or therapeutic intervention. It is solely based on the retrospective analysis of previously acquired CBCT scans from patients who have undergone root canal treatment. No drugs, devices, or procedures are administered or applied to participants as part of this study.

Primary outcomes

  1. Prevalence of Procedural Errors

    Time frame: Baseline assessment of all available cases within the study period

    Analysis of CBCT scans to detect and evaluate the prevalence of procedural errors such as instrument separation, perforations, ledges, and canal transportation in Endodontically treated teeth.

Secondary outcomes

  1. Distribution of Procedural Errors between Maxilla and Mandible

    Time frame: Baseline assessment of all available cases within the study period.

    Analysis of CBCT scans to determine and compare the distribution of procedural errors, such as instrument separation, perforations, ledges, and canal transportation, between maxillary and mandibular teeth.

Study contacts

Contact information is provided by the study sponsor or research team.

Esbah A. Mohamed, B.D.S /2018

CONTACT

[email protected]

00201094573196

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Prevalence of Endodontic Procedural Errors Using CBCT in an Egyptian Subpopulation: A Cross-Sectional Study

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 1, 2025
Registry last updated
Jul 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.